Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | CD44 | P16070 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18325510 | 0.87 | PNMT (0.46) | PNMTCD44MAOBHTR1AMEN1 | |
| SCHEMBL9139949 | 0.78 | HTR1A (0.53) | MAOBHTR1ACYP19A1MTNR1AMTNR1B | |
| SCHEMBL18325548 | 0.74 | PNMT (0.50) | PNMTCD44MAOBMEN1CYP3A4 | |
| SCHEMBL18325442 | 0.74 | PNMT (0.50) | PNMTCD44MAOBMEN1CYP3A4 | |
| SCHEMBL21505730 | 0.73 | PNMT (0.46) | PNMTHTR1AMTNR1AOPRM1OPRL1 | |
| SCHEMBL18322481 | 0.73 | PNMT (0.41) | PNMTCD44MAOBMEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL18706948 | 0.71 | PNMT (0.40) | PNMTCD44MAOBMEN1CYP3A4 | |
| SCHEMBL18325505 | 0.70 | PNMT (0.46) | PNMTCD44MAOBMEN1CYP3A4 | |
| SCHEMBL19158572 | 0.70 | MEN1 (0.49) | MEN1CYP3A4CYP2D6KMT2AHTR2C | |
| SCHEMBL10616682 | 0.68 | GBA1 (0.52) | MAOBHTR1ACYP3A4CYP2D6CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189042-B1 | TETRAHYDROISOQUINOLINE DERIVED PRMT5-INHIBITORS | CTXT PTY LTD (AU) | 2021-03-17 | — | — | EP | disclosed |