Sugi Predict

Sugi Predict / Compounds / SCHEMBL18327152

SCHEMBL18327152

SCHEMBL18327152

CC/C=C\C/C=C\C/C=C\CCCCCCC1CO1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.52
▸ F7 P08709 3/20 0.46
▸ F3 P13726 3/20 0.46
▸ CYP19A1 P11511 3/20 0.46
▸ MAPT P10636 2/20 0.46
▸ CYP3A4 P08684 2/20 0.46
▸ ALOX15 P16050 2/20 0.46
▸ HSD17B10 Q99714 2/20 0.46
▸ TDP1 Q9NUW8 2/20 0.46
▸ OXER1 Q8TDS5 2/20 0.46
▸ PTGS1 P23219 2/20 0.46
▸ PPARG P37231 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ PPARD Q03181 2/20 0.46
▸ PPARA Q07869 2/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ FFAR1 O14842 1/20 0.46
▸ NR1I2 O75469 1/20 0.46
▸ LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13883684 0.93 ALDH1A1 (0.54) ALDH1A1ENPP2LPAR2
SCHEMBL899230 0.89 ALDH1A1 (0.68) ALDH1A1ENPP2LPAR2
SCHEMBL18327149 0.89 ALDH1A1 (0.68) ALDH1A1ENPP2LPAR2
SCHEMBL899229 0.89 ALDH1A1 (0.68) ALDH1A1ENPP2LPAR2
SCHEMBL28910536 0.86 ALDH1A1 (0.62) ALDH1A1F7F3CYP19A1CYP3A4
SCHEMBL18327147 0.83 ALDH1A1 (0.76) ALDH1A1ENPP2LPAR2
SCHEMBL5839131 0.83 ALDH1A1 (0.76) ALDH1A1ENPP2LPAR2
SCHEMBL30958398 0.83 ALDH1A1 (0.76) ALDH1A1ENPP2LPAR2
SCHEMBL28705358 0.83 ALDH1A1 (0.63) ALDH1A1ENPP2LPAR2
SCHEMBL18327140 0.83 ALDH1A1 (0.76) ALDH1A1ENPP2LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029790-B2 Biomimetic nanomaterials and uses thereof OHIO STATE INNOVATION FOUNDATION (US) 2024-07-09 — — US disclosed
US-20230338577-A1 ALKENYL SUBSTITUTED 2,5-PIPERAZINEDIONES, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-10-26 — — US disclosed
US-11679165-B2 Alkenyl substituted 2,5-piperazinediones, compositions, and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-06-20 — — US disclosed
US-20160367686-A1 ALKENYL SUBSTITUTED 2,5-PIPERAZINEDIONES, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2016-12-22 — — US disclosed
US-20160367686-A1 ALKENYL SUBSTITUTED 2,5-PIPERAZINEDIONES, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2016-12-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12029790-B2 Biomimetic nanomaterials and uses thereof MTREX, HAVCR2, TSG101 ALDH1A1 2146/4885F7 3334/4885F3 3281/4885
US-11679165-B2 Alkenyl substituted 2,5-piperazinediones, compositions, and uses thereof UGT1A10, AKR1B10, CCR10 ALDH1A1 12/4885F7 1821/4885F3 969/4885
US-20160367686-A1 ALKENYL SUBSTITUTED 2,5-PIPERAZINEDIONES, COMPOSITIONS, AND USES THEREOF UGT1A10, AKR1B10, CCR10 ALDH1A1 12/4885F7 1821/4885F3 969/4885
US-20230338577-A1 ALKENYL SUBSTITUTED 2,5-PIPERAZINEDIONES, COMPOSITIONS, AND USES THEREOF UGT1A10, AKR1B10, CCR10 ALDH1A1 12/4885F7 1821/4885F3 969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.