SCHEMBL18327675

SCHEMBL18327675

CC1(C)CCC2(CCC(C)(C)c3cc(O)c(O)cc32)c2cc(O)c(O)cc21

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RXRA P19793 14/20 0.45
RARB P10826 9/20 0.42
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
RARG P13631 9/20 0.38
RARA P10276 7/20 0.38
RXRB P28702 9/20 0.37
RXRG P48443 8/20 0.37
CYP26A1 O43174 2/20 0.35
CYP26B1 Q9NR63 1/20 0.35
PPARG P37231 1/20 0.35
CYP3A4 P08684 1/20 0.34
CRABP2 P29373 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15347776 0.91 RXRA (0.50) RXRARARBTP53CYP1A2RARG
SCHEMBL196263 0.79 RXRA (0.35) RXRARARBTP53CYP1A2CYP3A4
SCHEMBL19101607 0.79 CYP1A2 (0.42) RXRARARBTP53CYP1A2RARG
SCHEMBL29569404 0.79 RXRA (0.35) RXRARARBTP53CYP1A2CYP3A4
SCHEMBL6224470 0.77 RXRA (0.46) RXRARARBTP53CYP1A2RARG
SCHEMBL21440625 0.77 RXRA (0.38) RXRARARBTP53RARGRARA
SCHEMBL23633278 0.77 ALDH1A1 (0.54) RXRARARBTP53CYP1A2RARG
SCHEMBL9867919 0.76 RXRA (0.44) RXRARARBTP53CYP1A2RARG
SCHEMBL7806009 0.76 RXRA (0.44) RXRARARBTP53CYP1A2RARG
SCHEMBL5846259 0.76 RXRA (0.46) RXRARARBTP53CYP1A2RARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230178848-A1 ELECTRODE SEPARATORS UNIV KING ABDULLAH SCI & TECH (SA) 2023-06-08 US disclosed
US-20230178848-A1 ELECTRODE SEPARATORS UNIV KING ABDULLAH SCI & TECH (SA) 2023-06-08 US disclosed
EP-3837038-B1 DIVERSITY-ORIENTED POLYMERS OF INTRINSIC MICROPOROSITY AND USES THEREOF UNIV CALIFORNIA (US) 2023-02-15 EP disclosed
US-20210309802-A1 DIVERSITY-ORIENTED POLYMERS OF INTRINSIC MICROPOROSITY AND USES THEREOF UNITED STATES DEPARTMENT OF ENERGY 2021-10-07 US disclosed
WO-2020037246-A1 DIVERSITY-ORIENTED POLYMERS OF INTRINSIC MICROPOROSITY AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-02-20 WO disclosed
US-20160367948-A1 CROSSLINKED POLYMER, METHOD FOR PRODUCING THE SAME, MOLECULAR SIEVE COMPOSITION AND MATERIAL SEPARATION MEMBRANES KYOTO UNIVERSITY (JP) 2016-12-22 US disclosed
US-20160367948-A1 CROSSLINKED POLYMER, METHOD FOR PRODUCING THE SAME, MOLECULAR SIEVE COMPOSITION AND MATERIAL SEPARATION MEMBRANES KYOTO UNIVERSITY (JP) 2016-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210309802-A1 DIVERSITY-ORIENTED POLYMERS OF INTRINSIC MICROPOROSITY AND USES THEREOF PARN, PARG, PAM RXRA 1355/4885RARB 747/4885TP53 4125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.