SCHEMBL5193549

SCHEMBL5193549

O=CC1C(=O)N(c2ccccc2)N(c2ccccc2)C1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.47
▸ PTGS1 P23219 2/20 0.47
▸ ABCB11 O95342 1/20 0.47
▸ FPR1 P21462 1/20 0.44
▸ GSK3A P49840 2/20 0.40
▸ GSK3B P49841 2/20 0.40
▸ ALDH1A1 P00352 3/20 0.39
▸ CYP3A4 P08684 2/20 0.39
▸ RAB9A P51151 2/20 0.39
▸ MAPT P10636 2/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ NAPRT Q6XQN6 1/20 0.39
▸ MEN1 O00255 4/20 0.38
▸ KMT2A Q03164 4/20 0.38
▸ MGLL Q99685 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18328092 0.83 TSHR (0.44) LMNAPTGS1ABCB11FPR1ALDH1A1
SCHEMBL18332636 0.79 TRIM24 (0.42) ALDH1A1MAPK1SMN1; SMN2KDM4E
SCHEMBL23295127 0.77 FPR1 (0.50) LMNAPTGS1ABCB11FPR1GSK3A
SCHEMBL12900984 0.73 LMNA (0.50) LMNAPTGS1ABCB11FPR1GSK3A
SCHEMBL11639145 0.73 LMNA (0.55) LMNAPTGS1ABCB11FPR1GSK3A
SCHEMBL3498051 0.71 ALDH1A1 (0.50) LMNAPTGS1ABCB11FPR1ALDH1A1
SCHEMBL18328089 0.71 KMT2A (0.42) GSK3AGSK3BALDH1A1RAB9AMAPT
SCHEMBL29951040 0.70 MEN1 (0.43) LMNAALDH1A1MAPTHPGDMEN1
SCHEMBL11285459 0.69 CYP3A4 (0.56) LMNAPTGS1ABCB11FPR1ALDH1A1
SCHEMBL20878207 0.69 LMNA (0.43) LMNAPTGS1ABCB11FPR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101151013-A Reducing colorant for keratin fibers PROCTER & GAMBLE (US) 2008-03-26 — — CN claimed
EP-1707187-B1 Reductive colorant for keratin fibres WELLA AG (DE) 2007-08-01 — — EP claimed
US-20060230548-A1 Reductive colorant for keratin fibres THE PROCTER & GAMBLE COMPANY 2006-10-19 — — US claimed
WO-2006107595-A1 REDUCTIVE COLORANT FOR KERATIN FIBRES THE PROCTER & GAMBLE COMPANY (US) 2006-10-12 — — WO claimed
EP-1707187-A1 Reductive colorant for keratin fibres Wella Aktiengesellschaft (DE) 2006-10-04 — — EP claimed
US-20230242490-A1 METHOD FOR THE PREPARATION OF SULFINPYRAZONE CHENGDA PHARMACEUTICALS CO., LTD. (CN) 2023-08-03 — — US disclosed
US-10254456-B2 Polarizing plate composition, polarizing plate protective film, polarizer, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2019-04-09 — — US disclosed
US-20160370523-A1 POLARIZING PLATE COMPOSITION, POLARIZING PLATE PROTECTIVE FILM, POLARIZER, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 — — US disclosed
US-20160370523-A1 POLARIZING PLATE COMPOSITION, POLARIZING PLATE PROTECTIVE FILM, POLARIZER, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 — — US disclosed
CN-101151013-A Reducing colorant for keratin fibers PROCTER & GAMBLE (US) 2008-03-26 — — CN disclosed
EP-1707187-B1 Reductive colorant for keratin fibres WELLA AG (DE) 2007-08-01 — — EP disclosed
US-20060230548-A1 Reductive colorant for keratin fibres THE PROCTER & GAMBLE COMPANY 2006-10-19 — — US disclosed
WO-2006107595-A1 REDUCTIVE COLORANT FOR KERATIN FIBRES THE PROCTER & GAMBLE COMPANY (US) 2006-10-12 — — WO disclosed
EP-1707187-A1 Reductive colorant for keratin fibres Wella Aktiengesellschaft (DE) 2006-10-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242490-A1 METHOD FOR THE PREPARATION OF SULFINPYRAZONE TST, DDT, STS LMNA 4870/4885PTGS1 1468/4885ABCB11 4431/4885
US-20060230548-A1 Reductive colorant for keratin fibres KRT18, COX6C, CYC1 LMNA 1014/4885PTGS1 1753/4885ABCB11 4685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback