SCHEMBL18328600

SCHEMBL18328600

CCC1OC(OCc2ccccc2)C(OCc2ccccc2)[C@@H](C)[C@H]1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGF1 P05230 2/20 0.43
FGF2 P09038 2/20 0.43
VEGFA P15692 2/20 0.43
HPSE Q9Y251 2/20 0.43
SSTR5 P35346 2/20 0.41
SSTR1 P30872 1/20 0.41
SSTR2 P30874 1/20 0.41
SSTR4 P31391 1/20 0.41
SSTR3 P32745 1/20 0.41
BCHE P06276 1/20 0.39
SLC6A2 P23975 1/20 0.39
PTPN1 P18031 6/20 0.38
CDC25B P30305 6/20 0.38
PDPK1 O15530 1/20 0.38
MTOR P42345 1/20 0.38
PTPN2 P17706 2/20 0.36
PTPN6 P29350 2/20 0.36
PTPN11 Q06124 2/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15504369 1.00 FGF1 (0.43) FGF1FGF2VEGFAHPSESSTR5
SCHEMBL17174992 0.92 SSTR5 (0.50) FGF1FGF2VEGFAHPSESSTR5
SCHEMBL16367561 0.92 SSTR5 (0.50) FGF1FGF2VEGFAHPSESSTR5
SCHEMBL14667229 0.91 SSTR1 (0.44) FGF1FGF2VEGFAHPSESSTR5
SCHEMBL14478887 0.88 SLC6A2 (0.36) FGF1FGF2VEGFAHPSESSTR5
SCHEMBL15280895 0.88 FGF1 (0.39) FGF1FGF2VEGFAHPSESSTR5
SCHEMBL18653425 0.87 SLC6A2 (0.44) FGF1FGF2VEGFAHPSESSTR5
SCHEMBL15871629 0.87 SSTR5 (0.51) FGF1FGF2VEGFAHPSESSTR5
SCHEMBL12136334 0.87 SLC6A2 (0.48) FGF1FGF2VEGFAHPSESSTR5
SCHEMBL18328601 0.87 SLC6A2 (0.48) FGF1FGF2VEGFAHPSESSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160367678-A1 BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF LAUREN SCIENCES LLC (US) 2016-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160367678-A1 BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF GFRA2, GFRA1, NGF FGF1 8/4885FGF2 14/4885VEGFA 166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.