Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF1 | P05230 | 2/20 | 0.39 |
| ▸ | FGF2 | P09038 | 2/20 | 0.39 |
| ▸ | VEGFA | P15692 | 2/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15504369 | 0.88 | FGF1 (0.43) | FGF1FGF2VEGFAHPSESSTR5 | |
| SCHEMBL18328600 | 0.88 | FGF1 (0.43) | FGF1FGF2VEGFAHPSESSTR5 | |
| SCHEMBL4404459 | 0.87 | SLC6A2 (0.40) | FGF1FGF2VEGFAHPSESSTR5 | |
| SCHEMBL16640651 | 0.87 | SLC6A2 (0.40) | FGF1FGF2VEGFAHPSESSTR5 | |
| SCHEMBL18718054 | 0.86 | SLC6A2 (0.44) | FGF1FGF2VEGFAHPSESLC6A2 | |
| SCHEMBL12920541 | 0.86 | FGF1 (0.43) | FGF1FGF2VEGFAHPSESSTR5 | |
| SCHEMBL14667229 | 0.85 | SSTR1 (0.44) | FGF1FGF2VEGFAHPSESSTR5 | |
| SCHEMBL17447101 | 0.83 | LGALS8 (0.43) | SLC6A2TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL17174992 | 0.82 | SSTR5 (0.50) | FGF1FGF2VEGFAHPSESSTR5 | |
| SCHEMBL16367561 | 0.82 | SSTR5 (0.50) | FGF1FGF2VEGFAHPSESSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9370529-B2 | Tannin inhibitors of HIV | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2016-06-21 | — | — | US | disclosed |
| US-20160038520-A1 | TANNIN INHIBITORS OF HIV | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2016-02-11 | — | — | US | disclosed |
| US-9181291-B2 | Tannin inhibitors of HIV | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2015-11-10 | — | — | US | disclosed |
| US-20130252909-A1 | TANNIN INHIBITORS OF HIV | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2013-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130252909-A1 | TANNIN INHIBITORS OF HIV | SERPINB1, TSN, FURIN | FGF1 4025/4885FGF2 4278/4885VEGFA 3515/4885 |
| US-20160038520-A1 | TANNIN INHIBITORS OF HIV | SERPINB1, TSN, FURIN | FGF1 4025/4885FGF2 4278/4885VEGFA 3515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.