SCHEMBL18329477

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23362891	0.87	PTGS2 (0.43)	PTGS2CA12CA1CA2CA7
	SCHEMBL18329542	0.85	CA12 (0.47)	CA12CA1CA2CA7CA9
	SCHEMBL1671329	0.83	CA12 (0.47)	CA12CA1CA2CA7CA9
	SCHEMBL8488636	0.82	ABL1 (0.45)	PTGS2CA12CA1CA2CA7
	SCHEMBL1495245	0.82	CA12 (0.50)	CA12CA1CA2CA7CA9
	SCHEMBL3205636	0.81	CA12 (0.44)	CA12CA1CA2CA7CA9
	SCHEMBL31284126	0.81	TSHR (0.40)	CA12CA1CA2CA7CA9
	SCHEMBL29570135	0.81	TSHR (0.40)	CA12CA1CA2CA7CA9
	SCHEMBL1164172	0.79	ALDH1A1 (0.48)	GAALMNAALDH1A1KDM4EHSD17B10
	SCHEMBL3829091	0.79	DPP4 (0.50)	PTGS2GAAALDH1A1KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.