Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.41 |
| ▸ | RORC | P51449 | 9/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18332148 | 0.91 | NOD2 (0.39) | NOD1NOD2RORCKDM4ETSHR | |
| SCHEMBL18331705 | 0.85 | NOD1 (0.47) | NOD1NOD2RORCKDM4ELMNA | |
| SCHEMBL18331337 | 0.85 | ALOX5 (0.38) | NOD1NOD2RORCKDM4ELMNA | |
| SCHEMBL18332408 | 0.83 | NOD1 (0.42) | NOD1NOD2KDM4ELMNATSHR | |
| SCHEMBL18332251 | 0.81 | ALOX5 (0.36) | NOD1NOD2RORCKDM4ELMNA | |
| SCHEMBL18331336 | 0.81 | ALOX5 (0.36) | NOD1NOD2RORCKDM4ELMNA | |
| SCHEMBL10004054 | 0.80 | NOD1 (0.51) | NOD1NOD2KDM4ELMNATSHR | |
| SCHEMBL18332156 | 0.80 | NOD1 (0.44) | NOD1NOD2KDM4ELMNATSHR | |
| SCHEMBL18332188 | 0.78 | NOD1 (0.41) | NOD1NOD2KDM4ELMNATSHR | |
| SCHEMBL10003474 | 0.78 | NOD1 (0.46) | NOD1NOD2KDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016204261-A1 | AMINOPYRAZOLE DERIVATIVES | 中外製薬株式会社 | 2016-12-22 | — | — | WO | disclosed |