Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18331717 | 1.00 | ALOX5 (0.38) | ALOX5GAASMN1; SMN2LMNATP53 | |
| SCHEMBL18332371 | 0.86 | ALOX5 (0.39) | ALOX5GAASMN1; SMN2LMNAKDM4E | |
| SCHEMBL18332260 | 0.86 | ALOX5 (0.40) | ALOX5SMN1; SMN2LMNATP53MAPT | |
| SCHEMBL18332192 | 0.84 | ALOX5 (0.38) | ALOX5GAASMN1; SMN2LMNAKDM4E | |
| SCHEMBL21572151 | 0.83 | HPGD (0.30) | — | |
| SCHEMBL18332193 | 0.82 | GAA (0.39) | ALOX5GAASMN1; SMN2PABPC1APOBEC3A | |
| SCHEMBL18332185 | 0.81 | NOD2 (0.44) | ALOX5GAASMN1; SMN2PABPC1APOBEC3A | |
| SCHEMBL18332131 | 0.81 | ALOX5 (0.36) | ALOX5SMN1; SMN2LMNAMAPTKDM4E | |
| SCHEMBL18332189 | 0.81 | ALOX5 (0.35) | ALOX5 | |
| SCHEMBL18332013 | 0.80 | ALOX5 (0.41) | ALOX5LMNATP53MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016204261-A1 | AMINOPYRAZOLE DERIVATIVES | 中外製薬株式会社 | 2016-12-22 | — | — | WO | disclosed |