Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18332185 | 0.85 | NOD2 (0.44) | GAASMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18332408 | 0.85 | NOD1 (0.42) | GAAMAPTL3MBTL1ALOX5 | |
| SCHEMBL18331717 | 0.82 | ALOX5 (0.38) | GAAMAPTSMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL18332126 | 0.82 | ALOX5 (0.38) | GAAMAPTSMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL16792487 | 0.78 | HTR6 (0.43) | MAPTSMN1; SMN2CYP2C9MEN1KMT2A | |
| SCHEMBL18332156 | 0.78 | NOD1 (0.44) | GAASMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL18331706 | 0.77 | NOD1 (0.41) | MAPTL3MBTL1ALOX5 | |
| SCHEMBL10004054 | 0.76 | NOD1 (0.51) | GAASMN1; SMN2L3MBTL1ALOX5 | |
| SCHEMBL20584087 | 0.76 | PTGDR2 (0.38) | GAAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10003324 | 0.76 | NOD2 (0.43) | MAPTSMN1; SMN2MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016204261-A1 | AMINOPYRAZOLE DERIVATIVES | 中外製薬株式会社 | 2016-12-22 | — | — | WO | disclosed |