Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 4/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.44 |
| ▸ | HTR6 | P50406 | 4/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18331687 | 0.91 | NOD2 (0.45) | NOD2NOD1HTR6ALOX5TSHR | |
| SCHEMBL10003723 | 0.87 | NOD2 (0.56) | NOD2NOD1HTR6ALOX5TSHR | |
| SCHEMBL18332167 | 0.86 | HRH3 (0.47) | NOD2NOD1ALOX5TSHRKDM4E | |
| SCHEMBL18332161 | 0.84 | GPR119 (0.47) | NOD2NOD1 | |
| SCHEMBL18332162 | 0.79 | NOD1 (0.51) | NOD2NOD1ALOX5TSHRKDM4E | |
| SCHEMBL10004188 | 0.78 | NOD2 (0.54) | NOD2NOD1HTR6ALOX5TSHR | |
| SCHEMBL18331685 | 0.78 | NOD2 (0.44) | NOD2NOD1ALOX5TSHRKDM4E | |
| SCHEMBL18332392 | 0.78 | NOD2 (0.44) | NOD2NOD1ALOX5TSHRLMNA | |
| SCHEMBL18332186 | 0.77 | NOD1 (0.49) | NOD2NOD1ALOX5TSHRKDM4E | |
| SCHEMBL18332173 | 0.77 | NOD2 (0.43) | NOD2NOD1ALOX5TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016204261-A1 | AMINOPYRAZOLE DERIVATIVES | 中外製薬株式会社 | 2016-12-22 | — | — | WO | disclosed |