SCHEMBL183336

SCHEMBL183336

CCOC(=O)C(=O)CC(C)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
LMNA P02545 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MAPT P10636 1/20 0.47
GLO1 Q04760 1/20 0.46
MGAM O43451 2/20 0.46
GAA P10253 2/20 0.46
SI P14410 2/20 0.46
MGAM2 Q2M2H8 2/20 0.46
EGLN1 Q9GZT9 1/20 0.43
NPSR1 Q6W5P4 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CYP2D6 P10635 1/20 0.41
FAAH O00519 2/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
SOAT1 P35610 1/20 0.40
POLB P06746 1/20 0.39
TRPA1 O75762 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL1996535 0.95 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10MAPTGLO1
SCHEMBL8804853 0.87 GAA (0.52) ALDH1A1LMNAHSD17B10MAPTGLO1
SCHEMBL11253654 0.82 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10MAPTGLO1
SCHEMBL17817681 0.82 GAA (0.48) ALDH1A1LMNAHSD17B10MAPTGLO1
SCHEMBL7633120 0.81 ALDH1A1 (0.47) ALDH1A1LMNAHSD17B10MAPTGLO1
SCHEMBL6129631 0.80 EGLN1 (0.54) ALDH1A1LMNAHSD17B10MAPTGLO1
SCHEMBL1680531 0.80 GAA (0.67) ALDH1A1LMNAHSD17B10MAPTGLO1
SCHEMBL1983275 0.79 MGAM (0.43) ALDH1A1LMNAHSD17B10MAPTGLO1
SCHEMBL28029720 0.79 ALOX15 (0.41) ALDH1A1LMNAHSD17B10MAPTGLO1
SCHEMBL17194942 0.79 MAPT (0.39) ALDH1A1LMNAHSD17B10MAPTGLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612400-B2 Pyrrolopyridine derivative preparation method ST PHARM CO., LTD. (KR) 2026-04-28 US claimed
EP-4276101-B1 PYRROLOPYRIDINE DERIVATIVE PREPARATION METHOD ST PHARM CO LTD (KR) 2026-03-04 EP claimed
US-20240317737-A1 PYRROLOPYRIDINE DERIVATIVE PREPARATION METHOD ST PHARM CO., LTD. (KR) 2024-09-26 US claimed
CN-118164955-A Novel acaricide and preparation method thereof 山东中新科农生命科技股份有限公司 2024-06-11 CN claimed
EP-4276101-A1 PYRROLOPYRIDINE DERIVATIVE PREPARATION METHOD ST Pharm Co., Ltd. (KR) 2023-11-15 EP claimed
CN-116970746-A Synthetic tanning agent containing hexabasic carbonyl and preparation method and application thereof 南京工业大学 2023-10-31 CN claimed
WO-2023195412-A1 LIGHT EMITTING ELEMENT, DISPLAY DEVICE, METHOD FOR PRODUCING NANOPARTICLE DISPERSION LIQUID, AND NANOPARTICLE DISPERSION LIQUID シャープディスプレイテクノロジー株式会社 2023-10-12 WO claimed
CN-116356085-A Aliphatic synthetic tanning agent containing hexabasic carbonyl and preparation method and application thereof 南京工业大学 2023-06-30 CN claimed
CN-116334320-A Aliphatic synthetic tanning agent containing multifunctional groups and preparation method and application thereof 南京工业大学 2023-06-27 CN claimed
CN-116219085-A Synthetic tanning agent containing multifunctional structure and preparation method and application thereof 南京工业大学 2023-06-06 CN claimed
CN-112940420-B Composite stabilizer for CPVC foaming and preparation method thereof 九江天盛塑料助剂有限公司 2022-09-13 CN claimed
CN-112940420-A Composite stabilizer for CPVC foaming and preparation method thereof 九江天盛塑料助剂有限公司 2021-06-11 CN claimed
CN-104893154-A Environmentally-friendly 90-DEG C polyvinyl chloride cable insulating material YANTAI SHUNLONG CHEMICAL TECHNOLOGY CO LTD 2015-09-09 CN claimed
CN-104830408-A Emulsified metal cutting fluid YANTAI SHUNLONG CHEMICAL ENGINEERING TECHNOLOGY CO LTD 2015-08-12 CN claimed
CN-102976942-A Preparation method of acetyl ethyl pyruvate UNIV ZHEJIANG TECHNOLOGY 2013-03-20 CN claimed
CN-102971261-A Silica remediation in water GEN ELECTRIC 2013-03-13 CN claimed
US-20030148487-A1 1,3-dicarbonyl-dioxygenase - a new c-c-bond cleaving enzyme CODEXIS, INC. 2003-08-07 US claimed
JP-10053587-A None JP disclosed
EP-0000541-A2 1H-Pyrimido-(4,5-c)-1,2-diazepines, methods for their preparation and compositions containing them; their use as intermediates for heterocyclic transformations. THE WELLCOME FOUNDATION LIMITED (GB) 1979-02-07 EP disclosed
US-4134987-A PYRAZOLE DERIVATIVES, FUNGICIDES HUPPATZ JOHN L 1979-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240317737-A1 PYRROLOPYRIDINE DERIVATIVE PREPARATION METHOD MAVS, DPYD, ITPA ALDH1A1 2350/4885LMNA 4003/4885HSD17B10 2669/4885
US-12612400-B2 Pyrrolopyridine derivative preparation method PNP, MAP2K4, MAP2K5 ALDH1A1 686/4885LMNA 3615/4885HSD17B10 482/4885
US-20030148487-A1 1,3-dicarbonyl-dioxygenase - a new c-c-bond cleaving enzyme ALDH7A1, CMBL, DDO ALDH1A1 86/4885LMNA 2918/4885HSD17B10 26/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.