Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 4/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18334079 | 0.84 | CRBN (0.38) | CRBNF2PRSS1 | |
| SCHEMBL18506549 | 0.68 | — | — | |
| SCHEMBL18501582 | 0.66 | NPC1 (0.31) | — | |
| SCHEMBL18923680 | 0.66 | NPC1 (0.31) | — | |
| SCHEMBL12944600 | 0.61 | ALDH1A1 (0.35) | CRBN | |
| SCHEMBL11617579 | 0.59 | PRKCA (0.47) | — | |
| SCHEMBL11659154 | 0.56 | F2 (0.40) | CRBNF2PRSS1 | |
| SCHEMBL2665515 | 0.56 | ALDH1A1 (0.50) | CRBN | |
| SCHEMBL6740222 | 0.55 | CRBN (0.56) | CRBNCASP3 | |
| SCHEMBL8758609 | 0.55 | CRBN (0.48) | CRBNF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10463644-B2 | Uses of sesquiterpene lactone compounds and their derivatives in drugs preparation | ACCENDATECH (CN) | 2019-11-05 | — | — | US | disclosed |
| US-20160367525-A1 | USES OF SESQUITERPENE LACTONE COMPOUNDS AND THEIR DERIVATIVES IN DRUGS PREPARATION | ACCENDATECH (CN) | 2016-12-22 | — | — | US | disclosed |
| US-20160367525-A1 | USES OF SESQUITERPENE LACTONE COMPOUNDS AND THEIR DERIVATIVES IN DRUGS PREPARATION | ACCENDATECH (CN) | 2016-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10463644-B2 | Uses of sesquiterpene lactone compounds and their derivatives in drugs preparation | MCL1, TNF, LSS | CRBN 2074/4885F2 2971/4885PRSS1 3623/4885 |
| US-20160367525-A1 | USES OF SESQUITERPENE LACTONE COMPOUNDS AND THEIR DERIVATIVES IN DRUGS PREPARATION | MCL1, TNF, LSS | CRBN 2074/4885F2 2971/4885PRSS1 3623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.