Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18334084 | 0.84 | CRBN (0.36) | CRBNF2PRSS1 | |
| SCHEMBL18334090 | 0.80 | ALOX5 (0.35) | F2PRSS1ALOX5 | |
| SCHEMBL4699124 | 0.60 | CRBN (0.54) | CRBN | |
| SCHEMBL7767198 | 0.59 | CRBN (0.49) | CRBN | |
| SCHEMBL7766813 | 0.58 | CYP1A2 (0.36) | CRBNF2PRSS1 | |
| SCHEMBL22532338 | 0.58 | CRBN (0.51) | CRBNDDB1 | |
| SCHEMBL7764865 | 0.58 | CRBN (0.45) | CRBN | |
| SCHEMBL566956 | 0.58 | CRBN (0.42) | CRBNF2PRSS1DDB1 | |
| SCHEMBL566957 | 0.58 | CRBN (0.42) | CRBNF2PRSS1DDB1 | |
| SCHEMBL19744406 | 0.58 | CRBN (0.46) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10463644-B2 | Uses of sesquiterpene lactone compounds and their derivatives in drugs preparation | ACCENDATECH (CN) | 2019-11-05 | — | — | US | disclosed |
| US-20160367525-A1 | USES OF SESQUITERPENE LACTONE COMPOUNDS AND THEIR DERIVATIVES IN DRUGS PREPARATION | ACCENDATECH (CN) | 2016-12-22 | — | — | US | disclosed |
| US-20160367525-A1 | USES OF SESQUITERPENE LACTONE COMPOUNDS AND THEIR DERIVATIVES IN DRUGS PREPARATION | ACCENDATECH (CN) | 2016-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10463644-B2 | Uses of sesquiterpene lactone compounds and their derivatives in drugs preparation | MCL1, TNF, LSS | CRBN 2074/4885F2 2971/4885PRSS1 3623/4885 |
| US-20160367525-A1 | USES OF SESQUITERPENE LACTONE COMPOUNDS AND THEIR DERIVATIVES IN DRUGS PREPARATION | MCL1, TNF, LSS | CRBN 2074/4885F2 2971/4885PRSS1 3623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.