Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | YAP1 | P46937 | 3/20 | 0.35 |
| ▸ | KLK7 | P49862 | 3/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18335145 | 0.85 | NR3C1 (0.35) | PTGESS1PR3 | |
| SCHEMBL18335060 | 0.84 | PTGES (0.37) | PTGES | |
| SCHEMBL18335153 | 0.82 | TRPA1 (0.36) | PTGESS1PR3 | |
| SCHEMBL18335078 | 0.78 | EGLN1 (0.39) | PTGES | |
| SCHEMBL18335135 | 0.75 | EGLN1 (0.40) | PTGES | |
| SCHEMBL18335169 | 0.74 | EGLN1 (0.40) | PTGES | |
| SCHEMBL18335084 | 0.73 | EGLN1 (0.38) | PTGES | |
| SCHEMBL18335062 | 0.71 | EGLN1 (0.41) | — | |
| SCHEMBL18335116 | 0.67 | EGLN1 (0.39) | PTGES | |
| SCHEMBL18335091 | 0.67 | P2RX7 (0.41) | PTGESCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10029986-B2 | Alkynyl pyridine-substituted amide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-07-24 | — | — | US | disclosed |
| US-20170008847-A1 | ALKYNYL PYRIDINE-SUBSTITUTED AMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-01-12 | — | — | US | disclosed |
| EP-3109234-A1 | ALKYNYLPYRIDINE-SUBSTITUTED AMIDE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2016-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10029986-B2 | Alkynyl pyridine-substituted amide compound and pesticide | CHRM1, CHRM2, CHRM3 | PTGES 3364/4885CTSS 2226/4885PPARA 2314/4885 |
| US-20170008847-A1 | ALKYNYL PYRIDINE-SUBSTITUTED AMIDE COMPOUND AND PESTICIDE | CHRM1, CHRM2, CHRM3 | PTGES 3364/4885CTSS 2226/4885PPARA 2314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.