Biphenyl

Biphenyl

SCHEMBL183386

Nc1nc(N)nc(N)n1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 7/20 0.75
ADORA1 P30542 6/20 0.75
ADORA3 P0DMS8 2/20 0.75
ADORA2B P29275 2/20 0.75
POLB P06746 1/20 0.75
ALDH1A1 P00352 2/20 0.56
CYP3A4 P08684 1/20 0.55
TAAR1 Q96RJ0 1/20 0.55
HSD17B10 Q99714 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
NUDT1 P36639 1/20 0.54
HSP90AA1 P07900 3/20 0.52
KDM4E B2RXH2 2/20 0.52
HSP90AB1 P08238 2/20 0.52
DHFR P00374 2/20 0.52
CSNK1A1 P48729 1/20 0.50
CLK4 Q9HAZ1 1/20 0.50
MEN1 O00255 1/20 0.50
CYP1A2 P05177 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6977514 0.87 ADORA1 (0.91) ADORA2AADORA1ADORA3ADORA2BPOLB
Benzoguanamine SCHEMBL28634836 0.86 ADORA2A (1.00) ADORA2AADORA1ADORA3ADORA2BPOLB
Benzoguanamine SCHEMBL27898 0.86 ADORA2A (1.00) ADORA2AADORA1ADORA3ADORA2BPOLB
Benzoguanamine SCHEMBL917182 0.86 ADORA2A (1.00) ADORA2AADORA1ADORA3ADORA2BPOLB
Biphenyl SCHEMBL8467751 0.85 ADORA1 (0.58) ADORA2AADORA1ADORA3ADORA2BPOLB
Benzoguanamine SCHEMBL8613754 0.84 ADORA2A (0.95) ADORA2AADORA1ADORA3ADORA2BPOLB
Biphenyl SCHEMBL27987857 0.84 ADORA2A (0.56) ADORA2AADORA1ADORA3ADORA2BPOLB
Benzoguanamine SCHEMBL29131394 0.84 ADORA2A (0.95) ADORA2AADORA1ADORA3ADORA2BPOLB
Benzoguanamine SCHEMBL11620040 0.84 ADORA2A (0.95) ADORA2AADORA1ADORA3ADORA2BPOLB
Benzene SCHEMBL19253562 0.83 ADORA2A (0.58) ADORA2AADORA1ADORA3ADORA2BPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118878801-B Phosphorus-nitrogen synergistic structure type flame-retardant PET and preparation method thereof 福建师范大学泉港石化研究院 2025-09-12 CN disclosed
US-20240174563-A1 FIRE- RESISTANT OVERLAYS, FIRE-RESISTANT PANELS, AND PROCESSES FOR MAKING AND USING SAME GP BUILDING PRODUCTS SERVICES LLC 2024-05-30 US disclosed
CN-116731469-A Polyacetal resin composition and molded article 旭化成株式会社 2023-09-12 CN disclosed
EP-4225712-A1 FIRE- RESISTANT OVERLAYS, FIRE-RESISTANT PANELS, AND PROCESSES FOR MAKING AND USING SAME GP Building Products Services LLC (US) 2023-08-16 EP disclosed
CN-110878167-B Polyacetal resin composition and metal resin composition 旭化成株式会社 2023-02-21 CN disclosed
US-11542370-B2 Aromatic alcohol-lignin-aldehyde resins and processes for making and using same Bakelite UK Holding Ltd. 2023-01-03 US disclosed
WO-2022201018-A1 FIRE- RESISTANT OVERLAYS, FIRE-RESISTANT PANELS, AND PROCESSES FOR MAKING AND USING SAME GP BUILDING PRODUCTS SERVICES LLC (US) 2022-09-29 WO disclosed
US-20210009764-A1 AROMATIC ALCOHOL-LIGNIN-ALDEHYDE RESINS AND PROCESSES FOR MAKING AND USING SAME JPMORGAN CHASE BANK, N.A. 2021-01-14 US disclosed
US-10738025-B2 Modified polyphenol binder compositions and methods for making and using same GEORGIA-PACIFIC CHEMICALS LLC (US) 2020-08-11 US disclosed
CN-106905544-B Manufacturing method, polyacetal resin composite particle and the formed body of polyacetals 旭化成株式会社 2019-08-23 CN disclosed
WO-2000078836-A1 CYCLIC UREA-FORMALDEHYDE PREPOLYMER-MODIFIED MELAMINE-CONTAINING RESINS, AND USE IN BINDERS FOR CELLULOSIC-BASED COMPOSITES GEORGIA-PACIFIC RESINS, INC. (US) 2000-12-28 WO disclosed
EP-1042382-A1 CYCLIC UREA-FORMALDEHYDE PREPOLYMER FOR USE IN PHENOL-FORMALDEHYDE AND MELAMINE-FORMALDEHYDE RESIN-BASED BINDERS GEORGIA-PACIFIC RESINS, INC. (US) 2000-10-11 EP disclosed
US-6114491-A FOR USE AS BINDER FOR CONSOLIDATED WOOD PRODUCTS SUCH AS PLYWOOD, ENGINEERED LUMBER, HARD BOARD, FIBER BOARD, ORIENTED STRAND BOARD, AND OTHER PRODUCTS SUCH AS FIBERGLASS INSULATION, LAMINATES, ABRASIVE COATINGS, FRICTION BINDERS GEORGIA-PACIFIC RESINS, INC. (US) 2000-09-05 US disclosed
US-6001925-A Melamine-formaldehyde resins modified with dicyandiamide and sorbitol for impregnation of substrates for post-formable decorative laminates GEORGIA-PACIFIC RESINS, INC. (US) 1999-12-14 US disclosed
WO-1999032534-A1 CYCLIC UREA-FORMALDEHYDE PREPOLYMER FOR USE IN PHENOL-FORMALDEHYDE AND MELAMINE-FORMALDEHYDE RESIN-BASED BINDERS GEORGIA-PACIFIC RESINS, INC. (US) 1999-07-01 WO disclosed
US-5820997-A Decorative high-pressure laminates made with thermosetting melamine resins modified with sorbitol GEORGIA-PACIFIC RESINS, INC. (US) 1998-10-13 US disclosed
US-5710239-A Water-soluble sulfonated melamine-formaldehyde resins GEORGIA-PACIFIC RESINS, INC. (US) 1998-01-20 US disclosed
US-5684118-A Method of scavenging formaldehyde using a low mole ratio melamine-urea-formaldehyde resin GEORGIA-PACIFIC RESINS, INC. (US) 1997-11-04 US disclosed
WO-1997039891-A1 DECORATIVE, HIGH-PRESSURE LAMINATES MADE WITH THERMOSETTING MELAMINE RESINS MODIFIED WITH SORBITOL GEORGIA-PACIFIC RESINS, INC. (US) 1997-10-30 WO disclosed
US-5681917-A UREA-FORMALDEHYDE RESIN IS FORMED FIRST, THEN MELAMINE IS ADDED AND ATTACHES TO URE-FROMALDEHYDE RESIN AND EXTEND THE POLYMER IN A CONTROLLED MOLE RATIOS AND PH CONDITIONS; REDUCES FORMALDEHYDE EMISSION GEORGIA-PACIFIC RESINS, INC. (US) 1997-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10738025-B2 Modified polyphenol binder compositions and methods for making and using same MYB, HLCS, KDM4C ADORA2A 4682/4885ADORA1 3971/4885ADORA3 4690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.