Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 5/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18347675 | 0.79 | KDM4E (0.37) | HPGDTSHRKDM4EALDH1A1NPSR1 | |
| SCHEMBL12658891 | 0.72 | LTB4R2 (0.68) | HPGDTSHRKDM4EALDH1A1NPSR1 | |
| SCHEMBL18347670 | 0.68 | MEN1 (0.41) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL18216887 | 0.66 | LMNA (0.56) | HPGDTSHRALDH1A1NPSR1MEN1 | |
| SCHEMBL12251783 | 0.65 | HPGD (0.72) | HPGDMEN1KMT2A | |
| SCHEMBL17774456 | 0.65 | ALOX5 (0.60) | HPGDLTB4R2MEN1KMT2A | |
| SCHEMBL11465092 | 0.64 | MLYCD (0.49) | HPGDTSHRKDM4EALDH1A1NPSR1 | |
| SCHEMBL14442982 | 0.64 | KMT2A (0.69) | HPGDTSHRKDM4EALDH1A1PSEN1 | |
| SCHEMBL18347659 | 0.63 | KDM4E (0.48) | HPGDTSHRKDM4EALDH1A1NPSR1 | |
| SCHEMBL20169254 | 0.63 | IDO1 (0.41) | HPGDTSHRKDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10766882-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | YUNGJIN PHARM CO., LTD. (KR) | 2020-09-08 | — | — | US | disclosed |
| US-9975883-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | YUNGJIN PHARM. CO., LTD. (KR) | 2018-05-22 | — | — | US | disclosed |
| US-9975883-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | YUNGJIN PHARM. CO., LTD. (KR) | 2018-05-22 | — | — | US | disclosed |
| US-20160376258-A1 | 1,2-NAPHTHOQUINONE BASED DERIVATIVE AND METHOD OF PREPARING THE SAME | KT&G LIFE SCIENCES CORPORATION (KR) | 2016-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10766882-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | CYP2S1, GYS2, SLC5A1 | HPGD 686/4885TSHR 2741/4885KDM4E 3755/4885 |
| US-20160376258-A1 | 1,2-NAPHTHOQUINONE BASED DERIVATIVE AND METHOD OF PREPARING THE SAME | CYP2S1, GYS2, SLC5A1 | HPGD 686/4885TSHR 2741/4885KDM4E 3755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.