Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11900441 | 0.80 | ALDH1A1 (0.70) | ALDH1A1HPGDGAAKMT2AMEN1 | |
| SCHEMBL18347689 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HPGDGAAKMT2AKDM4E | |
| SCHEMBL18347722 | 0.76 | RAB9A (0.43) | ALDH1A1HPGDGAAKMT2AMEN1 | |
| SCHEMBL18347704 | 0.75 | POLB (0.52) | ALDH1A1HPGDGAAKMT2AMEN1 | |
| SCHEMBL18347711 | 0.74 | SMN1; SMN2 (0.51) | ALDH1A1HPGDGAAKMT2AMEN1 | |
| SCHEMBL3290432 | 0.73 | HSD17B10 (0.56) | ALDH1A1HPGDGAAKMT2AMEN1 | |
| SCHEMBL27841831 | 0.73 | POLB (0.68) | ALDH1A1HPGDGAAKMT2AMEN1 | |
| SCHEMBL10573912 | 0.73 | MAPK1 (0.61) | ALDH1A1HPGDKMT2ASMN1; SMN2ATM | |
| SCHEMBL18347723 | 0.73 | L3MBTL1 (0.47) | ALDH1A1HPGDGAAKMT2AMEN1 | |
| SCHEMBL6169172 | 0.69 | MEN1 (0.83) | ALDH1A1HPGDGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10766882-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | YUNGJIN PHARM CO., LTD. (KR) | 2020-09-08 | — | — | US | disclosed |
| US-9975883-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | YUNGJIN PHARM. CO., LTD. (KR) | 2018-05-22 | — | — | US | disclosed |
| US-9975883-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | YUNGJIN PHARM. CO., LTD. (KR) | 2018-05-22 | — | — | US | disclosed |
| US-20160376258-A1 | 1,2-NAPHTHOQUINONE BASED DERIVATIVE AND METHOD OF PREPARING THE SAME | KT&G LIFE SCIENCES CORPORATION (KR) | 2016-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10766882-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | CYP2S1, GYS2, SLC5A1 | ALDH1A1 688/4885HPGD 686/4885GAA 983/4885 |
| US-20160376258-A1 | 1,2-NAPHTHOQUINONE BASED DERIVATIVE AND METHOD OF PREPARING THE SAME | CYP2S1, GYS2, SLC5A1 | ALDH1A1 688/4885HPGD 686/4885GAA 983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.