Cefditoren

Cefditoren

SCHEMBL183494

CO/N=C(/C(=O)NC1C(=O)N2C(C(=O)O)=C(/C=C/c3scnc3C)CS[C@H]12)c1csc(N)n1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.79
▸ ALDH1A1 P00352 2/20 0.79
▸ USP2 O75604 1/20 0.79
▸ CYP3A4 P08684 1/20 0.79
▸ HPGD P15428 1/20 0.79
▸ FAP Q12884 1/20 0.79
▸ NR1I2 O75469 5/20 0.66
▸ HTR2C P28335 1/20 0.66
▸ PPARG P37231 2/20 0.64
▸ SLC22A6 Q4U2R8 2/20 0.64
▸ SLC22A8 Q8TCC7 2/20 0.64
▸ SLC22A11 Q9NSA0 2/20 0.64
▸ ALB P02768 1/20 0.64
▸ TDP1 Q9NUW8 6/20 0.63
▸ APEX1 P27695 3/20 0.63
▸ APAF1 O14727 2/20 0.63
▸ LMNA P02545 2/20 0.63
▸ L3MBTL1 Q9Y468 2/20 0.63
▸ TSHR P16473 1/20 0.63
▸ PLCG1 P19174 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cefditoren SCHEMBL27465513 1.00 MAPT (0.79) MAPTALDH1A1USP2CYP3A4HPGD
Cefditoren SCHEMBL16072829 1.00 MAPT (0.79) MAPTALDH1A1USP2CYP3A4HPGD
Cefditoren SCHEMBL27465514 1.00 MAPT (0.79) MAPTALDH1A1USP2CYP3A4HPGD
Cefditoren SCHEMBL157719 1.00 MAPT (0.79) MAPTALDH1A1USP2CYP3A4HPGD
Cefditoren SCHEMBL37473 1.00 MAPT (0.79) MAPTALDH1A1USP2CYP3A4HPGD
Cefditoren SCHEMBL2925672 1.00 MAPT (0.79) MAPTALDH1A1USP2CYP3A4HPGD
Cefditoren SCHEMBL183495 1.00 MAPT (0.79) MAPTALDH1A1USP2CYP3A4HPGD
Cefditoren SCHEMBL13986532 1.00 MAPT (0.79) MAPTALDH1A1USP2CYP3A4HPGD
Cefditoren SCHEMBL1650584 1.00 MAPT (0.79) MAPTALDH1A1USP2CYP3A4HPGD
Cefditoren SCHEMBL1650656 0.99 MAPT (0.78) MAPTALDH1A1USP2CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0236231-B1 Novel cephem compounds MEIJI SEIKA KAISHA (JP) 1994-05-04 — — EP claimed
EP-0175610-B1 NEW CEPHALOSPORIN COMPOUNDS AND THE PRODUCTION THEREOF MEIJI SEIKA KAISHA LTD. (JP) 1990-08-29 — — EP claimed
US-4839350-A Cephalosporin compounds and the production thereof MEIJI SEIKA KAISHA, LTD. (JP) 1989-06-13 — — US claimed
EP-0175610-A2 New cephalosporin compounds and the production thereof MEIJI SEIKA KAISHA LTD. (JP) 1986-03-26 — — EP claimed
US-8648065-B2 Antibacterial medicinal composition of enhanced oral absorptivity MEIJI SEIKA PHARMA CO., LTD. (JP) 2014-02-11 — — US disclosed
EP-1051978-B1 CRYSTALLOGRAPHICALLY STABLE AMORPHOUS CEPHALOSPORIN COMPOSITIONS AND PROCESS FOR PRODUCING THE SAME MEIJI SEIKA PHARMA CO LTD (JP) 2012-08-22 — — EP disclosed
EP-1671635-B1 NONCRYSTALLINE ANTIBACTERIAL COMPOSITION CONTAINING CEFDITOREN PIVOXIL MEIJI SEIKA PHARMA CO LTD (JP) 2012-01-04 — — EP disclosed
EP-1555024-B1 ANTIBACTERIAL MEDICINAL COMPOSITION OF ENHANCED ORAL ABSORPTIVITY MEIJI SEIKA KAISHA (JP) 2010-09-29 — — EP disclosed
US-20080069879-A1 STABLE SOLID DOSAGE FORM CONTAINING AMORPHOUS CEFDITOREN PIVOXIL AND PROCESS FOR PREPARATION THEREOF RANBAXY LABORATORIES LIMITED (IN) 2008-03-20 — — US disclosed
US-20070053973-A1 Amorphous antibiotic composition comprising cefditoren pivoxil MEIJI SEIKA KAISHA, LTD. (JP) 2007-03-08 — — US disclosed
EP-1671635-A1 NONCRYSTALLINE ANTIBACTERIAL COMPOSITION CONTAINING CEFDITOREN PIVOXIL MEIJI SEIKA KAISHA LTD. (JP) 2006-06-21 — — EP disclosed
US-20060051411-A1 Antibacterial medicinal composition of enhanced oral absorptivity MEIJI SEIKA PHARMA CO., LTD. (JP) 2006-03-09 — — US disclosed
EP-1016665-A1 PROCESS FOR THE SELECTIVE PREPARATION OF Z-ISOMERS OF 3-(2-SUBSTITUTED VINYL)CEPHALOSPORINS Meiji Seika Kaisha, Ltd. (JP) 2000-07-05 — — EP disclosed
EP-0723965-A1 NOVEL CEPHALOSPORIN DERIVATIVE MEIJI SEIKA KAISHA LTD. (JP) 1996-07-31 — — EP disclosed
EP-0236231-B1 Novel cephem compounds MEIJI SEIKA KAISHA (JP) 1994-05-04 — — EP disclosed
EP-0175610-B1 NEW CEPHALOSPORIN COMPOUNDS AND THE PRODUCTION THEREOF MEIJI SEIKA KAISHA LTD. (JP) 1990-08-29 — — EP disclosed
US-4918068-A ACTIVE AGAINST GRAM POSITIVE BACTERIA MEIJI SEIKA KAISHA, LTD. (JP) 1990-04-17 — — US disclosed
US-4839350-A Cephalosporin compounds and the production thereof MEIJI SEIKA KAISHA, LTD. (JP) 1989-06-13 — — US disclosed
EP-0236231-A2 Novel cephem compounds MEIJI SEIKA KAISHA LTD. (JP) 1987-09-09 — — EP disclosed
EP-0175610-A2 New cephalosporin compounds and the production thereof MEIJI SEIKA KAISHA LTD. (JP) 1986-03-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060051411-A1 Antibacterial medicinal composition of enhanced oral absorptivity SI, SLC10A2, ELOVL6 MAPT 2773/4885ALDH1A1 3542/4885USP2 1780/4885
US-20070053973-A1 Amorphous antibiotic composition comprising cefditoren pivoxil CFD, PEPD, PEF1 MAPT 2041/4885ALDH1A1 3635/4885USP2 886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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