Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18350265 | 0.91 | MEN1 (0.40) | CHRNA7TSHRALDH1A1MAPK1MEN1 | |
| SCHEMBL18361784 | 0.88 | SMN1; SMN2 (0.46) | TSHRALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL18361797 | 0.71 | FAAH (0.41) | TSHRALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL16700446 | 0.67 | TEAD2 (0.41) | TSHRALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL16700430 | 0.63 | SMN1; SMN2 (0.47) | CHRNA7ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL3103714 | 0.63 | MAPT (0.51) | CHRNA7TSHRALDH1A1MAPK1NPC1 | |
| SCHEMBL2173892 | 0.62 | TSHR (0.57) | CHRNA7TSHRALDH1A1MAPK1NPC1 | |
| SCHEMBL8675227 | 0.61 | TSHR (0.47) | TSHRALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL14064300 | 0.61 | TSHR (0.44) | TSHRALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL28014535 | 0.61 | MAPT (0.52) | CHRNA7TSHRALDH1A1MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160376278-A1 | FUSED PYRAZOLE DERIVATIVE HAVING AUTOTAXIN INHIBITORY ACTIVITY | THE UNIVERSITY OF TOKYO (JP) | 2016-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376278-A1 | FUSED PYRAZOLE DERIVATIVE HAVING AUTOTAXIN INHIBITORY ACTIVITY | ENPP2, PRTN3, TPX2 | CHRNA7 1759/4885TSHR 672/4885ALDH1A1 4647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.