SCHEMBL18351214

SCHEMBL18351214

C=Cc1ccc(S(=O)(=O)Nc2c(C)cc(C)c(Nc3cccc4ccccc34)c2C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RECQL P46063 1/20 0.47
▸ KMT2A Q03164 6/20 0.45
▸ MEN1 O00255 5/20 0.45
▸ ALDH1A1 P00352 3/20 0.45
▸ MAPT P10636 1/20 0.45
▸ LMNA P02545 1/20 0.42
▸ HTT P42858 1/20 0.42
▸ HKDC1 Q2TB90 1/20 0.41
▸ KEAP1 Q14145 2/20 0.40
▸ MCL1 Q07820 2/20 0.40
▸ FFAR4 Q5NUL3 1/20 0.39
▸ NFE2L2 Q16236 1/20 0.39
▸ HSP90AA1 P07900 1/20 0.38
▸ CRHBP P24387 1/20 0.38
▸ CRHR2 Q13324 1/20 0.38
▸ G6PD P11413 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ PTPN2 P17706 1/20 0.38
▸ PTPN1 P18031 1/20 0.38
▸ PTPN5 P54829 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18351221 0.74 FFAR4 (0.45) KMT2AMEN1ALDH1A1MAPTMCL1
SCHEMBL14409331 0.74 ALDH1A1 (0.65) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL14409388 0.72 FFAR4 (0.70) KMT2AFFAR4POLBCYTH2
SCHEMBL11707749 0.72 TP53 (0.44) KMT2AMEN1ALDH1A1MAPTKEAP1
SCHEMBL17486853 0.71 BCHE (0.51) RECQLKMT2AMEN1ALDH1A1MAPT
SCHEMBL7536143 0.70 RECQL (0.71) RECQLKMT2AMEN1ALDH1A1MAPT
SCHEMBL7573136 0.70 KEAP1 (0.76) RECQLKMT2AMEN1ALDH1A1MAPT
SCHEMBL6733723 0.69 HSD17B10 (0.65) RECQLKMT2AMEN1ALDH1A1MAPT
Styrene SCHEMBL28396331 0.69 ALDH1A1 (0.58) RECQLKMT2AMEN1ALDH1A1MAPT
SCHEMBL18351203 0.68 RAPGEF4 (0.61) KMT2AMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation FUJIFILM CORPORATION (JP) 2019-07-16 — — US disclosed
US-20160376234-A1 COLORING CURABLE RESIN COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING DEVICE, IMAGE DISPLAY DEVICE, COMPOUND, AND CATION FUJIFILM CORPORATION (JP) 2016-12-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160376234-A1 COLORING CURABLE RESIN COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING DEVICE, IMAGE DISPLAY DEVICE, COMPOUND, AND CATION O60361, WDR12, SEM1 RECQL 402/4885KMT2A 1719/4885MEN1 3357/4885
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation O60361, WDR12, SEM1 RECQL 402/4885KMT2A 1719/4885MEN1 3357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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