Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | PPP5C | P53041 | 1/20 | 0.33 |
| ▸ | GJB2 | P29033 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19669024 | 0.98 | GBA1 (0.43) | GBA1MAPK1CHRM5CHRM1CHRM3 | |
| SCHEMBL18352198 | 0.98 | GBA1 (0.43) | GBA1MAPK1CHRM5CHRM1CHRM3 | |
| SCHEMBL22769140 | 0.88 | CHRM5 (0.39) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL16157294 | 0.88 | CHRM5 (0.39) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL16145424 | 0.81 | ALDH1A1 (0.39) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL16154497 | 0.81 | ALDH1A1 (0.39) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL16157280 | 0.81 | CHRM5 (0.33) | MAPK1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL14704264 | 0.81 | ALDH1A1 (0.39) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL14704213 | 0.80 | TK1 (0.43) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL24721233 | 0.80 | ALDH1A1 (0.41) | TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9534008-B2 | Small molecule compounds that control plant- and insect-pathogenic nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-01-03 | — | — | US | disclosed |