Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TK1 | P04183 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16154497 | 0.88 | ALDH1A1 (0.39) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL16145424 | 0.88 | ALDH1A1 (0.39) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL14704264 | 0.88 | ALDH1A1 (0.39) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL24721233 | 0.87 | ALDH1A1 (0.41) | TSHRTK1 | |
| SCHEMBL16154509 | 0.87 | ALDH1A1 (0.41) | TSHRTK1 | |
| SCHEMBL16084870 | 0.87 | ALDH1A1 (0.41) | TSHRTK1 | |
| SCHEMBL18352197 | 0.81 | GBA1 (0.41) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL16084863 | 0.80 | IGF2R (0.36) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL18352198 | 0.80 | GBA1 (0.43) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL19669024 | 0.80 | GBA1 (0.43) | CHRM5CHRM1CHRM3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9445596-B2 | Small molecule compounds for the control of nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-09-20 | — | — | US | disclosed |
| US-20140303360-A1 | Small Molecule Compounds for the Control of Nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303360-A1 | Small Molecule Compounds for the Control of Nematodes | MAVS, EMG1, PINK1 | CHRM5 2748/4885CHRM1 3842/4885CHRM3 1469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.