Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TK1 | P04183 | 2/20 | 0.34 |
| ▸ | IGF2R | P11717 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 4/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SELL | P14151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14704264 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TK1IGF2RTBXA2RPTGFR | |
| SCHEMBL30163856 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TK1IGF2RTBXA2RPTGFR | |
| SCHEMBL16154497 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TK1IGF2RTBXA2RPTGFR | |
| SCHEMBL30465054 | 0.99 | ALDH1A1 (0.41) | ALDH1A1TK1IGF2RTBXA2RPTGFR | |
| SCHEMBL16154509 | 0.99 | ALDH1A1 (0.41) | ALDH1A1TK1IGF2RTBXA2RPTGFR | |
| SCHEMBL24721233 | 0.99 | ALDH1A1 (0.41) | ALDH1A1TK1IGF2RTBXA2RPTGFR | |
| SCHEMBL29779648 | 0.99 | ALDH1A1 (0.41) | ALDH1A1TK1IGF2RTBXA2RPTGFR | |
| SCHEMBL16084870 | 0.99 | ALDH1A1 (0.41) | ALDH1A1TK1IGF2RTBXA2RPTGFR | |
| SCHEMBL16145439 | 0.99 | ALDH1A1 (0.41) | ALDH1A1TK1IGF2RTBXA2RPTGFR | |
| SCHEMBL30465046 | 0.99 | ALDH1A1 (0.41) | ALDH1A1TK1IGF2RTBXA2RPTGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9534008-B2 | Small molecule compounds that control plant- and insect-pathogenic nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-01-03 | — | — | US | disclosed |
| US-9487551-B2 | Small molecule compounds that control mammal-pathogenic nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-11-08 | — | — | US | disclosed |
| US-9445596-B2 | Small molecule compounds for the control of nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-09-20 | — | — | US | disclosed |
| US-20140364386-A1 | Small Molecule Compounds That Control Plant- and Insect-Pathogenic Nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-12-11 | — | — | US | disclosed |
| US-20140303102-A1 | Small Molecule Compounds that Control Mammal-Pathogenic Nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-10-09 | — | — | US | disclosed |
| US-20140303360-A1 | Small Molecule Compounds for the Control of Nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303360-A1 | Small Molecule Compounds for the Control of Nematodes | MAVS, EMG1, PINK1 | ALDH1A1 4656/4885TK1 3855/4885IGF2R 3605/4885 |
| US-20140364386-A1 | Small Molecule Compounds That Control Plant- and Insect-Pathogenic Nematodes | HNMT, EMG1, API5 | ALDH1A1 4581/4885TK1 4038/4885IGF2R 4557/4885 |
| US-20140303102-A1 | Small Molecule Compounds that Control Mammal-Pathogenic Nematodes | EMG1, HNMT, MSN | ALDH1A1 4056/4885TK1 4399/4885IGF2R 4369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.