Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 3/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18360049 | 0.93 | DHODH (0.34) | F2RDHODHSCN8ASCN10A | |
| SCHEMBL18354647 | 0.93 | TSHR (0.35) | TSHRF2RDHODHSCN8ASCN10A | |
| SCHEMBL18359812 | 0.93 | MAPT (0.35) | TSHRF2RDHODH | |
| SCHEMBL18354656 | 0.92 | DHODH (0.36) | F2RDHODH | |
| SCHEMBL18354530 | 0.92 | HTT (0.34) | TSHRF2RDHODHSCN8ASCN10A | |
| SCHEMBL18354413 | 0.91 | DHODH (0.37) | TSHRDHODH | |
| SCHEMBL18354409 | 0.90 | DHODH (0.33) | TSHRDHODH | |
| SCHEMBL18354192 | 0.90 | MAPT (0.36) | DHODH | |
| SCHEMBL18354702 | 0.89 | DHODH (0.37) | DHODH | |
| SCHEMBL18354526 | 0.89 | DHODH (0.37) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210051955-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-25 | — | — | US | disclosed |
| US-20200253205-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-13 | — | — | US | disclosed |
| US-20190075792-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-14 | — | — | US | disclosed |
| US-20180077930-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | US | disclosed |
| US-20180077930-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | US | disclosed |
| US-9839216-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-12 | — | — | US | disclosed |
| US-9839216-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-12 | — | — | US | disclosed |
| US-20170000120-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-05 | — | — | US | disclosed |
| US-20170000120-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200253205-A1 | INSECTICIDAL COMPOUNDS | ACHE, CYP4X1, ITPR3 | TSHR 3400/4885F2R 1728/4885DHODH 3024/4885 |
| US-20180077930-A1 | INSECTICIDAL COMPOUNDS | ACHE, CYP4X1, ITPR3 | TSHR 3400/4885F2R 1728/4885DHODH 3024/4885 |
| US-20210051955-A1 | INSECTICIDAL COMPOUNDS | ACHE, CYP4X1, ITPR3 | TSHR 3400/4885F2R 1728/4885DHODH 3024/4885 |
| US-20190075792-A1 | INSECTICIDAL COMPOUNDS | ACHE, CYP4X1, ITPR3 | TSHR 3400/4885F2R 1728/4885DHODH 3024/4885 |
| US-20170000120-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | TSHR 3588/4885F2R 1971/4885DHODH 3226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.