Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ATP4A | P20648 | 1/20 | 0.31 |
| ▸ | ATP4B | P51164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18354632 | 0.97 | MLYCD (0.36) | MLYCDALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL16863611 | 0.94 | MLYCD (0.34) | MLYCDALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL18355928 | 0.92 | MLYCD (0.35) | MLYCDDHODH | |
| SCHEMBL18354536 | 0.91 | MTTP (0.34) | ALDH1A1MAPTSMN1; SMN2NPC1LMNA | |
| SCHEMBL18354705 | 0.90 | MAPT (0.34) | ALDH1A1MAPTSMN1; SMN2NPC1LMNA | |
| SCHEMBL16870243 | 0.90 | MLYCD (0.34) | MLYCDALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL18355490 | 0.90 | MLYCD (0.37) | MLYCDALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL22332373 | 0.89 | MLYCD (0.36) | MLYCDALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL18354649 | 0.89 | LMNA (0.35) | ALDH1A1MAPTSMN1; SMN2NPC1LMNA | |
| SCHEMBL18354651 | 0.89 | MAPT (0.34) | ALDH1A1MAPTSMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9750246-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-05 | — | — | US | disclosed |
| US-9750246-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-05 | — | — | US | disclosed |
| US-20170000121-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-05 | — | — | US | disclosed |
| US-20170000121-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170000121-A1 | INSECTICIDAL COMPOUNDS | ACHE, NIT2, CHRM1 | MLYCD 3166/4885ALDH1A1 673/4885MAPT 4303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.