Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.72 |
| ▸ | HPGD | P15428 | 7/20 | 0.72 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | CA12 | O43570 | 1/20 | 0.72 |
| ▸ | CA1 | P00915 | 1/20 | 0.72 |
| ▸ | CA2 | P00918 | 1/20 | 0.72 |
| ▸ | CA4 | P22748 | 1/20 | 0.72 |
| ▸ | CA6 | P23280 | 1/20 | 0.72 |
| ▸ | CA7 | P43166 | 1/20 | 0.72 |
| ▸ | CA9 | Q16790 | 1/20 | 0.72 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | G6PD | P11413 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL7085411 | 1.00 | KDM4E (0.72) | KDM4EALDH1A1HPGDHMGB1SMN1; SMN2 | |
| Salicylic Acid SCHEMBL5195824 | 1.00 | KDM4E (0.72) | KDM4EALDH1A1HPGDHMGB1SMN1; SMN2 | |
| Salicylic Acid SCHEMBL4464042 | 1.00 | KDM4E (0.72) | KDM4EALDH1A1HPGDHMGB1SMN1; SMN2 | |
| Salicylic Acid SCHEMBL2450905 | 0.92 | ALDH1A1 (0.78) | KDM4EALDH1A1HPGDHMGB1SMN1; SMN2 | |
| Salicylic Acid SCHEMBL31230843 | 0.92 | ALDH1A1 (0.78) | KDM4EALDH1A1HPGDHMGB1SMN1; SMN2 | |
| Salicylic Acid SCHEMBL30340746 | 0.92 | ALDH1A1 (0.78) | KDM4EALDH1A1HPGDHMGB1SMN1; SMN2 | |
| Salicylic Acid SCHEMBL11590105 | 0.92 | ALDH1A1 (0.78) | KDM4EALDH1A1HPGDHMGB1SMN1; SMN2 | |
| Salicylic Acid SCHEMBL28399898 | 0.92 | ALDH1A1 (0.78) | KDM4EALDH1A1HPGDHMGB1SMN1; SMN2 | |
| Salicylic Acid SCHEMBL11512229 | 0.90 | ALDH1A1 (0.75) | KDM4EALDH1A1HPGDHMGB1SMN1; SMN2 | |
| Salicylic Acid SCHEMBL6063018 | 0.90 | KDM4E (0.82) | KDM4EALDH1A1HPGDHMGB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444431-A1 | SULFATE FREE PERSONAL CLEANSING COMPOSITION COMPRISING EFFECTIVE PRESERVATION | The Procter & Gamble Company (US) | 2024-10-16 | — | — | EP | claimed |
| CN-118265516-A | Sulfate-free personal cleansing compositions with effective preservation | 宝洁公司 | 2024-06-28 | — | — | CN | claimed |
| CN-117083072-A | Cosmetic composition | 奇华顿股份有限公司 | 2023-11-17 | — | — | CN | claimed |
| US-20230363380-A1 | INSTRINSICALLY ANTIMICROBIAL POROSIC MATRIX COMPOSITES AND METHOD OF MANUFACTURE THEREOF | WILSON JOHN PAUL (US) | 2023-11-16 | — | — | US | claimed |
| US-20230190606-A1 | SULFATE FREE PERSONAL CLEANSING COMPOSITION COMPRISING EFFECTIVE PRESERVATION | THE PROCTER & GAMBLE COMPANY | 2023-06-22 | — | — | US | claimed |
| WO-2023108097-A1 | SULFATE FREE PERSONAL CLEANSING COMPOSITION COMPRISING EFFECTIVE PRESERVATION | THE PROCTER & GAMBLE COMPANY (US) | 2023-06-15 | — | — | WO | claimed |
| US-20220079145-A1 | INSTRINSICALLY ANTIMICROBIAL POROSIC MATRIX COMPOSITES AND METHOD OF MANUFACTURE THEREOF | WILSON JOHN PAUL (US) | 2022-03-17 | — | — | US | claimed |
| CN-122095066-A | Enzyme stabilization in protease inhibitor-containing compositions | — | 2026-05-26 | — | — | CN | disclosed |
| EP-4728032-A1 | STABILIZED CLEANING COMPOSITIONS COMPRISING EDDS AND ENZYMES AND THEIR USE | BASF SE (DE) | 2026-04-22 | — | — | EP | disclosed |
| US-20260098231-A1 | DETERGENT COMPOSITIONS, POLYMERS AND METHODS OF MANUFACTURING THE SAME | BASF SE (DE) | 2026-04-09 | — | — | US | disclosed |
| EP-4716736-A1 | POLYMERS, AQUEOUS COMPOSITIONS COMPRISING SUCH POLYMERS, AND USE AS LAUNDRY DETERGENTS | BASF SE (DE) | 2026-04-01 | — | — | EP | disclosed |
| EP-4713425-A1 | POLYMERS, AQUEOUS COMPOSITIONS COMPRISING SUCH POLYMERS, AND USE AS LAUNDRY DETERGENTS | BASF SE (DE) | 2026-03-25 | — | — | EP | disclosed |
| EP-4473038-B1 | COMPOSITIONS COMPRISING POLYMERS, POLYMERS, AND THEIR USE | BASF SE (DE) | 2026-03-11 | — | — | EP | disclosed |
| US-20140187684-A1 | LIQUIDS | INNOVIA FILMS LIMITED (GB) | 2014-07-03 | — | — | US | disclosed |
| US-20110257433-A1 | LIQUIDS | THE UNIVERSITY OF YORK (GB) | 2011-10-20 | — | — | US | disclosed |
| EP-2322497-A1 | Ionic liquids comprising nitrogen containing cations | Innovia Films Limited (GB) | 2011-05-18 | — | — | EP | disclosed |
| US-20070185330-A1 | Liquids | THE UNIVERSITY OF YORK (GB) | 2007-08-09 | — | — | US | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-4692224-A | CARPACITOR ANODES | SPRAGUE ELECTRIC COMPANY (US) | 1987-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230190606-A1 | SULFATE FREE PERSONAL CLEANSING COMPOSITION COMPRISING EFFECTIVE PRESERVATION | PRSS3, PLP2, PRSS2 | KDM4E 2496/4885ALDH1A1 3763/4885HPGD 2252/4885 |
| US-20260098231-A1 | DETERGENT COMPOSITIONS, POLYMERS AND METHODS OF MANUFACTURING THE SAME | SGMS2, SGMS1, PHOSPHO1 | KDM4E 721/4885ALDH1A1 4535/4885HPGD 4220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.