Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.55 |
| ▸ | MDM4 | O15151 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13163967 | 0.91 | CASP3 (0.57) | CASP3MDM4TP53MDM2KMT2A | |
| SCHEMBL2313063 | 0.91 | CASP3 (0.57) | CASP3MDM4TP53MDM2KMT2A | |
| SCHEMBL29386346 | 0.91 | CASP3 (0.57) | CASP3MDM4TP53MDM2KMT2A | |
| SCHEMBL7423417 | 0.91 | CASP3 (0.57) | CASP3MDM4TP53MDM2KMT2A | |
| SCHEMBL29361981 | 0.91 | CASP3 (0.57) | CASP3MDM4TP53MDM2KMT2A | |
| SCHEMBL29423514 | 0.91 | CASP3 (0.57) | CASP3MDM4TP53MDM2KMT2A | |
| SCHEMBL9449850 | 0.88 | MDM4 (0.51) | CASP3MDM4TP53MDM2KMT2A | |
| SCHEMBL5969952 | 0.86 | MDM4 (0.54) | CASP3MDM4TP53MDM2KMT2A | |
| SCHEMBL22108945 | 0.86 | MDM4 (0.51) | CASP3MDM4TP53MDM2KMT2A | |
| SCHEMBL30660220 | 0.85 | MDM4 (0.50) | CASP3MDM4TP53MDM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3313858-B1 | METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT | UNIV GENT (BE) | 2019-09-25 | — | — | EP | disclosed |
| WO-2017001204-A1 | METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT | UNIVERSITEIT GENT (BE) | 2017-01-05 | — | — | WO | disclosed |