Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.58 |
| ▸ | CTSK | P43235 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14455148 | 0.86 | CTSS (0.57) | CTSSCTSKCA2EPHX2KLK7 | |
| SCHEMBL27483577 | 0.84 | CTSK (0.64) | CTSSCTSKCA2EPHX2KLK7 | |
| SCHEMBL27688713 | 0.84 | CTSK (0.64) | CTSSCTSKCA2EPHX2KLK7 | |
| SCHEMBL27704332 | 0.84 | CTSK (0.64) | CTSSCTSKCA2EPHX2KLK7 | |
| SCHEMBL15304537 | 0.84 | MEN1 (0.52) | CTSSCTSKCA2KLK7MEN1 | |
| SCHEMBL18354232 | 0.84 | MEN1 (0.46) | CTSSCTSKCA2MEN1GAA | |
| SCHEMBL13143969 | 0.83 | CTSK (0.60) | CTSSCTSKCA2EPHX2KLK7 | |
| SCHEMBL294929 | 0.83 | CTSS (0.63) | CTSSCTSKCA2EPHX2KLK7 | |
| SCHEMBL14301283 | 0.83 | CTSS (0.63) | CTSSCTSKCA2EPHX2KLK7 | |
| SCHEMBL478758 | 0.83 | CTSS (0.63) | CTSSCTSKCA2EPHX2KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10919840-B2 | Diamine crosslinking agents, crosslinked acidic polysaccharides and medical materials | SEIKAGAKU CORPORATION (JP) | 2021-02-16 | — | — | US | disclosed |
| EP-3101064-B1 | DIAMINE CROSSLINKING AGENT, ACIDIC POLYSACCHARIDE CROSSLINKED BODY, AND MEDICAL MATERIAL | SEIKAGAKU KOGYO CO LTD (JP) | 2020-07-15 | — | — | EP | disclosed |
| US-20190345312-A1 | DIAMINE CROSSLINKING AGENTS, CROSSLINKED ACIDIC POLYSACCHARIDES AND MEDICAL MATERIALS | SEIKAGAKU CORPORATION (JP) | 2019-11-14 | — | — | US | disclosed |
| US-10294195-B2 | Diamine crosslinking agents, crosslinked acidic polysaccharides and medical materials | SEIKAGAKU CORPORATION (JP) | 2019-05-21 | — | — | US | disclosed |
| US-20170001948-A1 | DIAMINE CROSSLINKING AGENTS, CROSSLINKED ACIDIC POLYSACCHARIDES AND MEDICAL MATERIALS | SEIKAGAKU CORPORATION (JP) | 2017-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10294195-B2 | Diamine crosslinking agents, crosslinked acidic polysaccharides and medical materials | SAT1, ACMSD, ADM2 | CTSS 4147/4885CTSK 4211/4885CA2 1986/4885 |
| US-20170001948-A1 | DIAMINE CROSSLINKING AGENTS, CROSSLINKED ACIDIC POLYSACCHARIDES AND MEDICAL MATERIALS | SAT1, ACMSD, ADM2 | CTSS 4147/4885CTSK 4211/4885CA2 1986/4885 |
| US-10919840-B2 | Diamine crosslinking agents, crosslinked acidic polysaccharides and medical materials | SAT1, ACMSD, ADM2 | CTSS 4147/4885CTSK 4211/4885CA2 1986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.