Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.57 |
| ▸ | CTSK | P43235 | 2/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18360341 | 0.86 | CTSS (0.58) | CTSSCTSKEPHX2KLK7CA2 | |
| SCHEMBL20789083 | 0.85 | CYP1A2 (0.50) | CTSSCTSKCA2ALDH1A1CYP1A2 | |
| SCHEMBL19384747 | 0.85 | CYP1A2 (0.50) | CTSSCTSKCA2ALDH1A1CYP1A2 | |
| SCHEMBL27483577 | 0.83 | CTSK (0.64) | CTSSCTSKEPHX2KLK7CA2 | |
| SCHEMBL27704332 | 0.83 | CTSK (0.64) | CTSSCTSKEPHX2KLK7CA2 | |
| SCHEMBL27688713 | 0.83 | CTSK (0.64) | CTSSCTSKEPHX2KLK7CA2 | |
| SCHEMBL13143969 | 0.82 | CTSK (0.60) | CTSSCTSKEPHX2KLK7CA2 | |
| SCHEMBL294929 | 0.82 | CTSS (0.63) | CTSSCTSKEPHX2KLK7CA2 | |
| SCHEMBL14301283 | 0.82 | CTSS (0.63) | CTSSCTSKEPHX2KLK7CA2 | |
| SCHEMBL478758 | 0.82 | CTSS (0.63) | CTSSCTSKEPHX2KLK7CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070160526-A1 | Detection, monitoring and treatment of cancer | THE OPEN UNIVERSITY (GB) | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070160526-A1 | Detection, monitoring and treatment of cancer | MUC1, CA14, LGALS4 | CTSS 4038/4885CTSK 3135/4885EPHX2 4732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.