Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.62 |
| ▸ | CTSK | P43235 | 8/20 | 0.62 |
| ▸ | CTSB | P07858 | 2/20 | 0.62 |
| ▸ | CTSL | P07711 | 1/20 | 0.62 |
| ▸ | IDO1 | P14902 | 1/20 | 0.60 |
| ▸ | AKT1 | P31749 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.57 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283706 | 0.91 | KLK5 (0.59) | CTSSCTSKCTSBCTSLIDO1 | |
| SCHEMBL7283491 | 0.89 | ACE (0.61) | CTSSCTSKCTSBCTSLIDO1 | |
| SCHEMBL25528563 | 0.88 | CTSK (0.61) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL17492351 | 0.88 | CTSS (0.61) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL17492350 | 0.88 | CTSS (0.61) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL28461905 | 0.86 | CTSS (0.60) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL20118441 | 0.86 | CTSS (0.60) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL13335848 | 0.86 | ACE (0.61) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL16459752 | 0.86 | CTSS (0.68) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL16459753 | 0.86 | CTSS (0.68) | CTSSCTSKCTSBCTSLAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10919840-B2 | Diamine crosslinking agents, crosslinked acidic polysaccharides and medical materials | SEIKAGAKU CORPORATION (JP) | 2021-02-16 | — | — | US | disclosed |
| EP-3101064-B1 | DIAMINE CROSSLINKING AGENT, ACIDIC POLYSACCHARIDE CROSSLINKED BODY, AND MEDICAL MATERIAL | SEIKAGAKU KOGYO CO LTD (JP) | 2020-07-15 | — | — | EP | disclosed |
| US-20190345312-A1 | DIAMINE CROSSLINKING AGENTS, CROSSLINKED ACIDIC POLYSACCHARIDES AND MEDICAL MATERIALS | SEIKAGAKU CORPORATION (JP) | 2019-11-14 | — | — | US | disclosed |
| US-10294195-B2 | Diamine crosslinking agents, crosslinked acidic polysaccharides and medical materials | SEIKAGAKU CORPORATION (JP) | 2019-05-21 | — | — | US | disclosed |
| US-20170001948-A1 | DIAMINE CROSSLINKING AGENTS, CROSSLINKED ACIDIC POLYSACCHARIDES AND MEDICAL MATERIALS | SEIKAGAKU CORPORATION (JP) | 2017-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10294195-B2 | Diamine crosslinking agents, crosslinked acidic polysaccharides and medical materials | SAT1, ACMSD, ADM2 | CTSS 4147/4885CTSK 4211/4885CTSB 4284/4885 |
| US-20170001948-A1 | DIAMINE CROSSLINKING AGENTS, CROSSLINKED ACIDIC POLYSACCHARIDES AND MEDICAL MATERIALS | SAT1, ACMSD, ADM2 | CTSS 4147/4885CTSK 4211/4885CTSB 4284/4885 |
| US-10919840-B2 | Diamine crosslinking agents, crosslinked acidic polysaccharides and medical materials | SAT1, ACMSD, ADM2 | CTSS 4147/4885CTSK 4211/4885CTSB 4284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.