Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 7/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 4/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18361832 | 0.87 | LOXL2 (0.44) | LOXL2KDR | |
| SCHEMBL20337881 | 0.86 | ALDH1A1 (0.49) | LOXL2PPARGPPARAKMT2AALDH1A1 | |
| SCHEMBL18362016 | 0.86 | LOXL2 (0.73) | LOXL2KDM4EALDH1A1 | |
| SCHEMBL18361808 | 0.85 | LOXL2 (0.45) | LOXL2PPARGPPARAKDRKMT2A | |
| SCHEMBL18362172 | 0.83 | LOXL2 (0.42) | LOXL2KDRKMT2AMEN1MCL1 | |
| SCHEMBL18362073 | 0.82 | LOXL2 (0.74) | LOXL2PPARGPPARAPPARDMCL1 | |
| SCHEMBL18361806 | 0.79 | LOXL2 (0.39) | LOXL2PPARGPPARAKDRPPARD | |
| SCHEMBL20337854 | 0.79 | LOXL2 (0.39) | LOXL2PPARGPPARAKDRKMT2A | |
| SCHEMBL18049301 | 0.75 | LOXL2 (0.52) | LOXL2PPARGPPARAPPARDKDM4E | |
| SCHEMBL18361822 | 0.74 | LOXL2 (0.74) | LOXL2PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017003862-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2017-01-05 | — | — | WO | disclosed |