Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 3/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17526315 | 0.87 | SIRT6 (0.45) | KISS1RFOLH1CPB2SIRT1SIRT6 | |
| SCHEMBL16342128 | 0.85 | FOLH1 (0.46) | FOLH1SIRT1SIRT6SIRT5SMN1; SMN2 | |
| SCHEMBL14525109 | 0.82 | KISS1R (0.47) | KISS1RFOLH1CPB2SIRT1SIRT6 | |
| SCHEMBL9976417 | 0.82 | KISS1R (0.47) | KISS1RFOLH1CPB2SIRT1SIRT6 | |
| SCHEMBL10026152 | 0.82 | KISS1R (0.47) | KISS1RFOLH1CPB2SIRT1SIRT6 | |
| SCHEMBL24155382 | 0.82 | KISS1R (0.45) | KISS1RFOLH1CPB2SIRT1SIRT6 | |
| SCHEMBL24155383 | 0.82 | KISS1R (0.45) | KISS1RFOLH1CPB2SIRT1SIRT6 | |
| SCHEMBL24235573 | 0.82 | KISS1R (0.41) | KISS1RFOLH1CPB2SIRT1SIRT6 | |
| SCHEMBL24155380 | 0.82 | KISS1R (0.45) | KISS1RFOLH1CPB2SIRT1SIRT6 | |
| SCHEMBL16221913 | 0.82 | KISS1R (0.45) | KISS1RFOLH1CPB2SIRT1SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170000924-A1 | E-POLYLYSINE HYDROGEL AND PREPARATION METHOD AND APPLICATION THEREOF | NANJING TECH UNIVERSITY (CN) | 2017-01-05 | — | — | US | disclosed |