Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18362334 | 0.87 | KISS1R (0.43) | SIRT6SIRT1KISS1RSIRT5FOLH1 | |
| SCHEMBL13595628 | 0.87 | FOLH1 (0.54) | SIRT6SIRT1KISS1RSIRT5FOLH1 | |
| SCHEMBL21673279 | 0.87 | FOLH1 (0.54) | SIRT6SIRT1KISS1RSIRT5FOLH1 | |
| SCHEMBL14947853 | 0.85 | SIRT6 (0.50) | SIRT6SIRT1KISS1RSIRT5FOLH1 | |
| SCHEMBL10408291 | 0.85 | KDM4E (0.56) | SIRT6SIRT1SIRT5FOLH1SMN1; SMN2 | |
| SCHEMBL11887166 | 0.85 | KDM4E (0.56) | SIRT6SIRT1SIRT5FOLH1SMN1; SMN2 | |
| SCHEMBL9976417 | 0.84 | KISS1R (0.47) | SIRT6SIRT1KISS1RSIRT5FOLH1 | |
| SCHEMBL14525109 | 0.84 | KISS1R (0.47) | SIRT6SIRT1KISS1RSIRT5FOLH1 | |
| SCHEMBL10026152 | 0.84 | KISS1R (0.47) | SIRT6SIRT1KISS1RSIRT5FOLH1 | |
| SCHEMBL24155380 | 0.84 | KISS1R (0.45) | SIRT6SIRT1KISS1RSIRT5FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137765-A1 | TRANSITION-METAL CATALYST COMPOSITIONS AND METHODS FOR SEQUENCING BY SYNTHESIS | ILLUMINA, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024003087-A1 | FLUORESCENT DYES CONTAINING FUSED TETRACYCLIC BIS-BORON HETEROCYCLE AND USES IN SEQUENCING | ILLUMINA, INC. (US) | 2024-01-04 | — | — | WO | disclosed |
| WO-2023232829-A1 | COMPOSITIONS AND METHODS FOR NUCLEIC ACID SEQUENCING | ILLUMINA, INC (US) | 2023-12-07 | — | — | WO | disclosed |
| WO-2023186819-A1 | CHROMENOQUINOLINE DYES AND USES IN SEQUENCING | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023192900-A1 | NUCLEOSIDES AND NUCLEOTIDES WITH 3' VINYL BLOCKING GROUP USEFUL IN SEQUENCING BY SYNTHESIS | ILLUMINA SINGAPORE PTE. LTD. (SG) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023186982-A1 | COMPOSITIONS AND METHODS FOR IMPROVING SEQUENCING SIGNALS | ILLUMINA, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023186815-A1 | LABELED AVIDIN AND METHODS FOR SEQUENCING | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-10-05 | — | — | WO | disclosed |
| US-20230304086-A1 | LABELED AVIDIN AND METHODS FOR SEQUENCING | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-09-28 | — | — | US | disclosed |
| WO-2022136402-A1 | METHODS AND COMPOSITIONS FOR NUCLEIC ACID SEQUENCING | ILLUMINA CAMBRIDGE LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |
| WO-2022129930-A1 | ALKYLPYRIDINIUM COUMARIN DYES AND USES IN SEQUENCING APPLICATIONS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022129439-A1 | METHODS, SYSTEMS AND COMPOSITIONS FOR NUCLEIC ACID SEQUENCING | ILLUMINA CAMBRIDGE LIMITED (GB) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022129437-A1 | LONG STOKES SHIFT CHROMENOQUINOLINE DYES AND USES IN SEQUENCING APPLICATIONS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2022-06-23 | — | — | WO | disclosed |
| WO-2021259881-A1 | NUCLEOSIDES AND NUCLEOTIDES WITH 3' ACETAL BLOCKING GROUP | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-12-30 | — | — | WO | disclosed |
| WO-2021104845-A1 | CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-06-03 | — | — | WO | disclosed |
| EP-3564252-B1 | MODIFIED NUCLEOTIDE LINKERS | ILLUMINA CAMBRIDGE LTD (GB) | 2021-03-17 | — | — | EP | disclosed |
| WO-2020193765-A1 | METHODS AND COMPOSITIONS FOR NUCLEIC ACID SEQUENCING USING PHOTOSWITCHABLE LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2020-10-01 | — | — | WO | disclosed |
| WO-2020136170-A2 | NUCLEOSIDES AND NUCLEOTIDES WITH 3'-HYDROXY BLOCKING GROUPS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2020-07-02 | — | — | WO | disclosed |
| EP-3564252-A1 | MODIFIED NUCLEOTIDE LINKERS | Illumina Cambridge Limited (GB) | 2019-11-06 | — | — | EP | disclosed |
| EP-2780039-B9 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER (US) | 2018-04-18 | — | — | EP | disclosed |
| US-20160040225-A1 | MODIFIED NUCLEOTIDE LINKERS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160040225-A1 | MODIFIED NUCLEOTIDE LINKERS | RNGTT, DTYMK, DPYD | SIRT6 863/4885SIRT1 1530/4885KISS1R 3504/4885 |
| US-20230304086-A1 | LABELED AVIDIN AND METHODS FOR SEQUENCING | ANXA6, ANXA3, BCDIN3D | SIRT6 3723/4885SIRT1 4729/4885KISS1R 3453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.