SCHEMBL183630

SCHEMBL183630

Cc1cc(CO)c(C=O)o1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 2/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37
AOX1 Q06278 1/20 0.37
ALOX5 P09917 1/20 0.36
TRIM24 O15164 1/20 0.36
TRIM33 Q9UPN9 1/20 0.36
TSHR P16473 1/20 0.35
NQO1 P15559 1/20 0.34
GLA P06280 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.32
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31
MCL1 Q07820 1/20 0.31
SHBG P04278 1/20 0.31
ERN1 O75460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16231356 0.83 CA1 (0.38) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL3100001 0.73
SCHEMBL183359 0.71 ALOX5 (0.35) ALDH1A1MEN1KMT2AKDM4EALOX5
SCHEMBL5591713 0.71
SCHEMBL28227078 0.71 TDP1 (0.37) ALDH1A1MEN1KMT2AKDM4ELMNA
SCHEMBL6626531 0.70
SCHEMBL4372628 0.70 KDM4E (0.39) ALDH1A1MEN1KMT2AKDM4ELMNA
SCHEMBL9483022 0.69 ALDH1A1 (0.42) ALDH1A1MEN1KMT2AKDM4ELMNA
SCHEMBL28088888 0.69 ALDH1A1 (0.36) ALDH1A1MEN1KMT2AKDM4ELMNA
SCHEMBL28557816 0.69 ERN1 (0.38) ALDH1A1MEN1KMT2AKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011096812-A1 METHOD AND APPARATUS FOR MODIFYING WOOD, AND WOOD PRODUCT VIA INGENIO B.V. (NL) 2011-08-11 WO claimed
EP-2035198-A1 METHOD FOR MODIFYING WOOD AND WOOD THEREBY OBTAINED Transfurans Chemicals (BE) 2009-03-18 EP claimed
WO-2007147804-A1 METHOD FOR MODIFYING WOOD AND WOOD THEREBY OBTAINED TRANSFURANS CHEMICALS (BE) 2007-12-27 WO claimed
US-20150374667-A1 Compositions And Method For Treatment Of Ischemic Neuronal Reperfusion Injury HOWARD UNIVERSITY 2015-12-31 US disclosed
EP-2621979-B1 BIOCOMPOSITE PANEL ROEMMLER H RESOPAL WERK GMBH (DE) 2015-05-06 EP disclosed
US-20130295399-A1 BIOCOMPOSITE PANEL RESOPAL GMBH (DE) 2013-11-07 US disclosed
EP-2621979-A1 BIOCOMPOSITE PANEL RESOPAL GMBH (DE) 2013-08-07 EP disclosed
US-8158206-B2 Method for modifying wood and wood thereby obtained TRANSFURANS CHEMICALS (BE) 2012-04-17 US disclosed
WO-2012041521-A1 BIOCOMPOSITE PANEL RESOPAL GMBH (DE) 2012-04-05 WO disclosed
EP-2035198-B1 METHOD FOR MODIFYING WOOD AND WOOD THEREBY OBTAINED TRANSFURANS CHEMICALS (BE) 2012-01-04 EP disclosed
WO-2011096812-A1 METHOD AND APPARATUS FOR MODIFYING WOOD, AND WOOD PRODUCT VIA INGENIO B.V. (NL) 2011-08-11 WO disclosed
US-20100062276-A1 METHOD FOR MODIFYING WOOD AND WOOD THEREBY OBTAINED TRANSFURANS CHEMICALS (BE) 2010-03-11 US disclosed
EP-2035198-A1 METHOD FOR MODIFYING WOOD AND WOOD THEREBY OBTAINED Transfurans Chemicals (BE) 2009-03-18 EP disclosed
WO-2007147804-A1 METHOD FOR MODIFYING WOOD AND WOOD THEREBY OBTAINED TRANSFURANS CHEMICALS (BE) 2007-12-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150374667-A1 Compositions And Method For Treatment Of Ischemic Neuronal Reperfusion Injury BDNF, GAP43, BAX ALDH1A1 3292/4885MEN1 3653/4885KMT2A 4472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.