Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16560287 | 0.83 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDAOX1TRIM24 | |
| SCHEMBL13643406 | 0.79 | KDM4E (0.36) | KDM4EALDH1A1MEN1LMNAHPGD | |
| SCHEMBL21632238 | 0.79 | KDM4E (0.43) | KDM4EALDH1A1MEN1LMNAHPGD | |
| SCHEMBL13306818 | 0.77 | CYP1A2 (0.47) | KDM4EALDH1A1MEN1LMNAHPGD | |
| SCHEMBL4367756 | 0.77 | KDM4E (0.42) | KDM4EALDH1A1MEN1LMNAHPGD | |
| SCHEMBL29954339 | 0.75 | KDM4E (0.54) | KDM4EALDH1A1MEN1LMNAHPGD | |
| SCHEMBL19499649 | 0.75 | SRC (0.49) | KDM4EALDH1A1HPGDAOX1TRIM24 | |
| SCHEMBL27871739 | 0.73 | SRC (0.46) | KDM4EALDH1A1MEN1LMNAHPGD | |
| SCHEMBL2601956 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1HPGDAOX1TRIM24 | |
| SCHEMBL19411067 | 0.72 | ERN1 (0.42) | KDM4EALDH1A1MEN1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120107886-A1 | Lignin Oxidation and Products Thereof | STRATEGIC ENZYME APPLICATIONS, INC. (US) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107886-A1 | Lignin Oxidation and Products Thereof | LOX, LPO, NOX4 | KDM4E 512/4885ALDH1A1 263/4885MEN1 4885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.