SCHEMBL18364469

SCHEMBL18364469

CC(=O)c1nc(C(=O)O)n[nH]1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CGAS Q8N884 1/20 0.35
LMNA P02545 1/20 0.33
HCAR2 Q8TDS4 3/20 0.32
DAO P14920 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6771598 0.73
SCHEMBL15331401 0.70
SCHEMBL15552380 0.69 ALPL (0.49) LMNA
SCHEMBL3086461 0.68
SCHEMBL23382047 0.64 HSD17B10 (0.54) LMNA
SCHEMBL18832392 0.64 PIN1 (0.30)
SCHEMBL17501768 0.61
SCHEMBL11969830 0.59
Hydrochloric Acid SCHEMBL2032392 0.58 TSHR (0.36) LMNAHCAR2
Potassium SCHEMBL30932480 0.58 TSHR (0.36) LMNAHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170008915-A1 ACID, SOLVENT, AND THERMAL RESISTANT METAL-ORGANIC FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2017-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170008915-A1 ACID, SOLVENT, AND THERMAL RESISTANT METAL-ORGANIC FRAMEWORKS HAO2, ASF1A, FTO CGAS 411/4885LMNA 4321/4885HCAR2 2283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.