Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9456756 | 0.75 | MAPT (0.58) | MAPTPKMHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL17280952 | 0.72 | GPR3 (0.42) | MAPTLMNAALDH1A1POLBTSHR | |
| SCHEMBL9456268 | 0.72 | MAPT (0.51) | MAPTPKMHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL7435710 | 0.72 | PKM (0.58) | MAPTPKMHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL9447444 | 0.71 | PKM (0.61) | MAPTPKMHSD17B10SMN1; SMN2LMNA | |
| Bromide SCHEMBL7435341 | 0.71 | PKM (0.57) | MAPTPKMHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL1436118 | 0.71 | MAPT (0.50) | MAPTPKMHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL18074272 | 0.70 | CASP3 (0.67) | MAPTPKMHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL6699936 | 0.70 | GLS (0.71) | MAPTSMN1; SMN2CASP3GLSRAB9A | |
| SCHEMBL31612252 | 0.70 | PKM (0.52) | MAPTPKMHSD17B10SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10029986-B2 | Alkynyl pyridine-substituted amide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-07-24 | — | — | US | disclosed |
| US-20170008847-A1 | ALKYNYL PYRIDINE-SUBSTITUTED AMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10029986-B2 | Alkynyl pyridine-substituted amide compound and pesticide | CHRM1, CHRM2, CHRM3 | MAPT 4070/4885PKM 4056/4885HSD17B10 1699/4885 |
| US-20170008847-A1 | ALKYNYL PYRIDINE-SUBSTITUTED AMIDE COMPOUND AND PESTICIDE | CHRM1, CHRM2, CHRM3 | MAPT 4070/4885PKM 4056/4885HSD17B10 1699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.