Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18378770 | 0.86 | ENPP2 (0.51) | ENPP2ACKR3ALDH1A1PLA2G2CGRIN2D | |
| SCHEMBL15803290 | 0.78 | ACKR3 (0.47) | ENPP2ACKR3ALDH1A1HRH3KDM5A | |
| SCHEMBL15803267 | 0.74 | ACKR3 (0.45) | ENPP2ACKR3ALDH1A1HRH3 | |
| SCHEMBL15803293 | 0.73 | ACKR3 (0.44) | ENPP2ACKR3ALDH1A1HRH3 | |
| SCHEMBL7090846 | 0.73 | ALDH1A1 (0.59) | ACKR3ALDH1A1F10 | |
| SCHEMBL18472512 | 0.72 | ACKR3 (0.53) | ACKR3ALDH1A1HRH3KDM5AF10 | |
| SCHEMBL7088489 | 0.72 | ACKR3 (0.52) | ACKR3ALDH1A1HRH3F10 | |
| SCHEMBL2168920 | 0.72 | KDM6B (0.62) | ENPP2ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL15803472 | 0.71 | ACKR3 (0.47) | ACKR3ALDH1A1HRH3KDM5AF10 | |
| SCHEMBL15803275 | 0.71 | ACKR3 (0.45) | ENPP2ACKR3ALDH1A1HRH3KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170007614-A1 | Autotaxin inhibitors | NOVARTIS AG (CH) | 2017-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170007614-A1 | Autotaxin inhibitors | ENPP2, SERPINB1, TFPI | ENPP2 1/4885ACKR3 3781/4885ALDH1A1 4843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.