Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | CTSC | P53634 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449032 | 0.89 | KMT2A (0.54) | NPSR1KMT2AKDM4ELNPEPMDM4 | |
| SCHEMBL20415585 | 0.89 | TERT (0.51) | TERTKDM4ECTSCHTR2CHTR2B | |
| SCHEMBL30487484 | 0.84 | HTR2C (0.53) | TERTKDM4ECTSCHTR2CHTR2B | |
| SCHEMBL29630432 | 0.82 | TERT (0.48) | TERTCTSCHTR2CHTR2B | |
| SCHEMBL27538884 | 0.81 | CTSC (0.49) | NPSR1KMT2AKDM4ELNPEPNLRP3 | |
| SCHEMBL27538881 | 0.81 | CTSC (0.49) | NPSR1KMT2AKDM4ELNPEPNLRP3 | |
| SCHEMBL27515492 | 0.80 | CTSC (0.48) | NPSR1KMT2AKDM4ELNPEPNLRP3 | |
| SCHEMBL27515493 | 0.80 | CTSC (0.48) | NPSR1KMT2AKDM4ELNPEPNLRP3 | |
| SCHEMBL30487449 | 0.80 | CTSC (0.57) | TERTKDM4ECTSCHTR2CHTR2B | |
| SCHEMBL30052990 | 0.80 | CTSC (0.57) | TERTKDM4ECTSCHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230018246-A1 | PYRROLIDINE CARBOXAMIDO DERIVATIVES AND METHODS FOR PREPARING AND USING THE SAME | Research & Business Foundation Sungkyunkwan University (KR) | 2023-01-19 | — | — | US | disclosed |
| US-11365215-B2 | Method for preventing, improving, or treating inflammatory bowel disease | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2022-06-21 | — | — | US | disclosed |
| US-20180208625-A1 | METHOD FOR PREVENTING, IMPROVING, OR TREATING INFLAMMATORY BOWEL DISEASE | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2018-07-26 | — | — | US | disclosed |
| US-20170008924-A1 | PYRROLIDINE CARBOXAMIDO DERIVATIVES AND METHODS FOR PREPARING AND USING THE SAME | Research & Business Foundation Sungkyunkwan University (KR) | 2017-01-12 | — | — | US | disclosed |
| WO-2017008033-A1 | PYRROLIDINE CARBOXAMIDO DERIVATIVES AND METHODS FOR PREPARING AND USING THE SAME | Reasearch & Business Foundation Sungkyunkwan University (KR) | 2017-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180208625-A1 | METHOD FOR PREVENTING, IMPROVING, OR TREATING INFLAMMATORY BOWEL DISEASE | SI, NOD2, TNF | TERT 4178/4885NPSR1 2066/4885KMT2A 4521/4885 |
| US-20170008924-A1 | PYRROLIDINE CARBOXAMIDO DERIVATIVES AND METHODS FOR PREPARING AND USING THE SAME | NOD2, SI, APC | TERT 3505/4885NPSR1 2805/4885KMT2A 3249/4885 |
| US-11365215-B2 | Method for preventing, improving, or treating inflammatory bowel disease | SI, NOD2, TNF | TERT 4178/4885NPSR1 2066/4885KMT2A 4521/4885 |
| US-20230018246-A1 | PYRROLIDINE CARBOXAMIDO DERIVATIVES AND METHODS FOR PREPARING AND USING THE SAME | NOD2, SI, APC | TERT 3505/4885NPSR1 2805/4885KMT2A 3249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.