Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5661288 | 1.00 | SIGMAR1 (0.40) | SIGMAR1MCHR1SLC6A2KDM4ECYP2D6 | |
| SCHEMBL5663844 | 0.89 | SIGMAR1 (0.39) | SIGMAR1MCHR1SLC6A2KDM4ENCF1 | |
| SCHEMBL13209122 | 0.88 | KDM4E (0.41) | KDM4ECYP2D6HRH1KCNH2NCF1 | |
| SCHEMBL23275893 | 0.84 | MAPT (0.36) | SIGMAR1 | |
| SCHEMBL13939978 | 0.82 | SIGMAR1 (0.41) | SIGMAR1MCHR1SLC6A2KDM4ENCF1 | |
| SCHEMBL5661285 | 0.81 | SIGMAR1 (0.40) | SIGMAR1MCHR1SLC6A2KDM4ENCF1 | |
| SCHEMBL17263306 | 0.79 | SIGMAR1 (0.40) | SIGMAR1MCHR1SLC6A2KDM4ENCF1 | |
| SCHEMBL23603446 | 0.79 | SIGMAR1 (0.40) | SIGMAR1MCHR1SLC6A2KDM4ENCF1 | |
| SCHEMBL19226484 | 0.79 | PGR (0.43) | SIGMAR1MCHR1SLC6A2PGR | |
| SCHEMBL24027442 | 0.79 | TSHR (0.44) | SIGMAR1MCHR1KDM4ECYP2D6NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170008888-A1 | HETEROCYCLIC COMPOUNDS | ACTIVX BIOSCIENCES, INC. | 2017-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008888-A1 | HETEROCYCLIC COMPOUNDS | BET1, EP300, RBBP5 | SIGMAR1 4629/4885MCHR1 4734/4885SLC6A2 4800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.