SCHEMBL18379301

SCHEMBL18379301

CCCCCCCCCCCCN1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(c1ccc(CN(C)C)cc1)C5=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.55
▸ HIF1A Q16665 1/20 0.55
▸ TERT O14746 4/20 0.51
▸ FGFR1 P11362 2/20 0.44
▸ KDR P35968 2/20 0.44
▸ PDGFRA P16234 1/20 0.44
▸ KDM4E B2RXH2 3/20 0.42
▸ ALDH1A1 P00352 3/20 0.42
▸ POLB P06746 2/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ ACHE P22303 7/20 0.40
▸ MAOB P27338 3/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ NPC1 O15118 2/20 0.40
▸ LMNA P02545 2/20 0.40
▸ PABPC1 P11940 2/20 0.40
▸ KMT2A Q03164 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18379032 0.84 STAT3 (0.46) STAT3HIF1ATERTFGFR1KDR
SCHEMBL18379162 0.84 POLB (0.56) STAT3HIF1ATERTFGFR1KDR
SCHEMBL18378993 0.84 STAT3 (0.50) STAT3HIF1ATERTFGFR1KDR
SCHEMBL22651653 0.83 STAT3 (0.37) STAT3HIF1ATERTFGFR1KDR
SCHEMBL18379210 0.82 HTR1A (0.48) STAT3HIF1ATERTKDM4EALDH1A1
SCHEMBL18379189 0.82 HTR1A (0.48) STAT3HIF1ATERTKDM4EALDH1A1
SCHEMBL18379021 0.82 STAT3 (0.48) STAT3HIF1ATERTFGFR1KDR
SCHEMBL18379137 0.82 STAT3 (0.65) STAT3HIF1ATERTFGFR1KDR
SCHEMBL284967 0.82 STAT3 (0.65) STAT3HIF1ATERTFGFR1KDR
SCHEMBL8071104 0.82 STAT3 (0.65) STAT3HIF1ATERTFGFR1KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11022592-B2 Chemical self-doping of one-dimensional organic nanomaterials for high conductivity application in chemiresistive sensing gas or vapor UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2021-06-01 — — US disclosed
US-20180201612-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES UNIVERSITY OF UTAH 2018-07-19 — — US disclosed
US-20180201612-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES UNIVERSITY OF UTAH 2018-07-19 — — US disclosed
WO-2017142609-A2 CHEMICAL SELF-DOPING OF ONE-DIMENSIONAL ORGANIC NANOMATERIALS FOR HIGH CONDUCTIVITY APPLICATION IN CHEMIRESISTIVE SENSING GAS OR VAPOR UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2017-08-24 — — WO disclosed
US-20170160252-A1 CHEMICAL SELF-DOPING OF ONE-DIMENSIONAL ORGANIC NANOMATERIALS FOR HIGH CONDUCTIVITY APPLICATION IN CHEMIRSISTIVE SENSING GAS OR VAPOR UNIVERSITY OF UTAH 2017-06-08 — — US disclosed
US-20170160252-A1 CHEMICAL SELF-DOPING OF ONE-DIMENSIONAL ORGANIC NANOMATERIALS FOR HIGH CONDUCTIVITY APPLICATION IN CHEMIRSISTIVE SENSING GAS OR VAPOR UNIVERSITY OF UTAH 2017-06-08 — — US disclosed
WO-2017008074-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2017-01-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170160252-A1 CHEMICAL SELF-DOPING OF ONE-DIMENSIONAL ORGANIC NANOMATERIALS FOR HIGH CONDUCTIVITY APPLICATION IN CHEMIRSISTIVE SENSING GAS OR VAPOR DRD1, DRD4, DNER STAT3 1719/4885HIF1A 1831/4885TERT 806/4885
US-11022592-B2 Chemical self-doping of one-dimensional organic nanomaterials for high conductivity application in chemiresistive sensing gas or vapor DRD1, DRD2, DNER STAT3 1876/4885HIF1A 2131/4885TERT 839/4885
US-20180201612-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES NCS1, DAXX, CNDP2 STAT3 4101/4885HIF1A 3544/4885TERT 3724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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