SCHEMBL22651653

SCHEMBL22651653

CCCCCCCCCCCCN1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1O)c64)C(=O)N(c1ccc(CN(C)C)cc1)C5=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.37
▸ HIF1A Q16665 1/20 0.37
▸ TERT O14746 2/20 0.36
▸ POLB P06746 4/20 0.36
▸ KDM4E B2RXH2 4/20 0.36
▸ ALDH1A1 P00352 4/20 0.36
▸ TDP1 Q9NUW8 2/20 0.36
▸ CYP1A2 P05177 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ CYP2C19 P33261 1/20 0.36
▸ ALOX15 P16050 1/20 0.34
▸ FGFR1 P11362 2/20 0.33
▸ KDR P35968 2/20 0.33
▸ PDGFRA P16234 1/20 0.33
▸ APAF1 O14727 1/20 0.33
▸ FAAH O00519 1/20 0.32
▸ MGLL Q99685 1/20 0.32
▸ MEN1 O00255 2/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22651728 0.87 KDM4E (0.36) STAT3HIF1ATERTPOLBKDM4E
SCHEMBL18379301 0.83 STAT3 (0.55) STAT3HIF1ATERTPOLBKDM4E
SCHEMBL20392828 0.81 STAT3 (0.48) STAT3HIF1ATERTPOLBKDM4E
SCHEMBL22651727 0.80 STAT3 (0.41) STAT3HIF1ATERTPOLBKDM4E
SCHEMBL22651618 0.80 STAT3 (0.39) STAT3HIF1ATERTPOLBKDM4E
SCHEMBL22651631 0.78 ALDH1A1 (0.41) TERTPOLBKDM4EALDH1A1ALOX15
SCHEMBL23425474 0.78 TERT (0.40) TERTKDM4EALDH1A1MEN1KMT2A
SCHEMBL23987286 0.77 HEXA (0.44) STAT3HIF1ATERTPOLBKDM4E
SCHEMBL23425475 0.76 HDAC6 (0.43) TERTKDM4EALDH1A1TDP1HPGD
SCHEMBL23957124 0.76 HDAC3 (0.35) STAT3HIF1ATERTPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200354356-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES UNIVERSITY OF UTAH 2020-11-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354356-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES NCS1, DAXX, CNDP2 STAT3 4101/4885HIF1A 3544/4885TERT 3724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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