SCHEMBL18385939

SCHEMBL18385939

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nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ MAPT P10636 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.34
▸ HIF1A Q16665 1/20 0.34
▸ CD209 Q9NNX6 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ LGALS8 O00214 2/20 0.31
▸ SYNJ2 O15056 2/20 0.31
▸ GAA P10253 1/20 0.30
▸ TYR P14679 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18392791 1.00 L3MBTL1 (0.39) L3MBTL1MAPTALDH1A1HIF1ACD209
SCHEMBL20381805 1.00 L3MBTL1 (0.39) L3MBTL1MAPTALDH1A1HIF1ACD209
SCHEMBL25222379 1.00 L3MBTL1 (0.39) L3MBTL1MAPTALDH1A1HIF1ACD209
SCHEMBL25585820 1.00 L3MBTL1 (0.39) L3MBTL1MAPTALDH1A1HIF1ACD209
SCHEMBL19036942 0.90 ALDH1A1 (0.33) L3MBTL1MAPTALDH1A1HIF1A
SCHEMBL16201890 0.90 ALDH1A1 (0.33) L3MBTL1MAPTALDH1A1HIF1A
SCHEMBL16201903 0.90 ALDH1A1 (0.33) L3MBTL1MAPTALDH1A1HIF1A
SCHEMBL20381837 0.84 LGALS8 (0.34) L3MBTL1CD209LGALS8
SCHEMBL18393028 0.84 LGALS8 (0.34) L3MBTL1CD209LGALS8
SCHEMBL13482776 0.83 LGALS8 (0.43) L3MBTL1MAPTALDH1A1HIF1ACD209

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10023603-B2 Preparation of monosaccharides, disaccharides, trisaccharides, and pentasaccharides of heparinoids FORMOSA LABORATORIES, INC. (TW) 2018-07-17 — — US disclosed
US-20170015695-A1 PREPARATION OF MONOSACCHARIDES, DISACCHARIDES, TRISACCHARIDES, AND PENTASACCHARIDES OF HEPARINOIDS FORMOSA LABORATORIES, INC. (TW) 2017-01-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10023603-B2 Preparation of monosaccharides, disaccharides, trisaccharides, and pentasaccharides of heparinoids HPSE, DDOST, FUT5 L3MBTL1 4817/4885MAPT 4502/4885ALDH1A1 3929/4885
US-20170015695-A1 PREPARATION OF MONOSACCHARIDES, DISACCHARIDES, TRISACCHARIDES, AND PENTASACCHARIDES OF HEPARINOIDS HPSE, DDOST, FUT5 L3MBTL1 4817/4885MAPT 4502/4885ALDH1A1 3929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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