Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.60 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.60 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11989038 | 0.80 | ALDH1A1 (0.61) | BCHETRPC3TRPC4TRPC5SMN1; SMN2 | |
| SCHEMBL5133337 | 0.78 | LMNA (0.53) | BCHETRPC3TRPC4TRPC5SMN1; SMN2 | |
| SCHEMBL22619945 | 0.75 | BCHE (1.00) | BCHETRPC3TRPC4TRPC5SMN1; SMN2 | |
| SCHEMBL8464091 | 0.74 | BCHE (0.82) | BCHETRPC3TRPC4TRPC5SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL23295188 | 0.74 | BCHE (0.97) | BCHETRPC3TRPC4TRPC5SMN1; SMN2 | |
| SCHEMBL12472842 | 0.74 | BCHE (0.71) | BCHETRPC3TRPC4TRPC5SMN1; SMN2 | |
| SCHEMBL19733290 | 0.74 | ALDH1A1 (0.55) | BCHETRPC3TRPC4TRPC5SMN1; SMN2 | |
| SCHEMBL989750 | 0.73 | BCHE (0.60) | BCHETRPC3TRPC4TRPC5SMN1; SMN2 | |
| SCHEMBL6756155 | 0.73 | TAAR1 (0.56) | SMN1; SMN2RAB9ANPC1ALDH1A1DDAH1 | |
| SCHEMBL8779898 | 0.73 | LMNA (0.59) | SMN1; SMN2RAB9ANPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9550000-B2 | Compositions, methods, and systems for the synthesis and use of imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-01-24 | — | — | US | disclosed |