Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.60 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.60 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.60 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991498 | 0.91 | ALOX12 (0.53) | BCHETRPC3TRPC4TRPC5RAB9A | |
| SCHEMBL30175772 | 0.87 | BCHE (0.57) | BCHETRPC3TRPC4TRPC5RAB9A | |
| SCHEMBL28983300 | 0.87 | BCHE (0.57) | BCHETRPC3TRPC4TRPC5RAB9A | |
| SCHEMBL28983301 | 0.87 | BCHE (0.57) | BCHETRPC3TRPC4TRPC5RAB9A | |
| SCHEMBL3541921 | 0.82 | RAB9A (0.62) | BCHETRPC3TRPC4TRPC5RAB9A | |
| SCHEMBL14025138 | 0.81 | BCHE (0.71) | BCHETRPC3TRPC4TRPC5RAB9A | |
| SCHEMBL12472842 | 0.81 | BCHE (0.71) | BCHETRPC3TRPC4TRPC5RAB9A | |
| Hydrochloric Acid SCHEMBL27647756 | 0.79 | BCHE (0.69) | BCHETRPC3TRPC4TRPC5RAB9A | |
| SCHEMBL15360239 | 0.79 | BCHE (0.52) | BCHETRPC3TRPC4TRPC5RAB9A | |
| SCHEMBL5984336 | 0.78 | RIPK1 (0.62) | RAB9ASMN1; SMN2TP53RIPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104114539-B | Process for the stereoselective preparation of pyrazole carboxamides | 先正达参股股份有限公司 | 2016-10-12 | — | — | CN | disclosed |
| US-7897622-B2 | 2-amido-5-oxo/thio-benzoic acid derivatives; hepatitis C virus infection; synergistic with another inhibitor of HCV polymerase or immunomodulatory agent such as interferons | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-01 | — | — | US | disclosed |
| US-7863310-B2 | Kinase inhibitors | ELI LILLY AND COMPANY (US) | 2011-01-04 | — | — | US | disclosed |
| US-20080227839-A1 | Kinase Inhibitors | ELI LILLY AND COMPANY | 2008-09-18 | — | — | US | disclosed |
| US-20080045516-A1 | Viral Polymerase Inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227839-A1 | Kinase Inhibitors | ABL1, MAP3K20, MAP3K19 | BCHE 4475/4885TRPC3 3124/4885TRPC4 4066/4885 |
| US-20080045516-A1 | Viral Polymerase Inhibitors | POLR2A, POLR2H, POLR2E | BCHE 3897/4885TRPC3 4752/4885TRPC4 4833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.