Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27404415 | 0.80 | HSD17B1 (0.49) | PYGLHSD17B1HSD17B2ALDH1A1CYP1A2 | |
| SCHEMBL10487477 | 0.79 | PRMT1 (0.69) | ALDH1A1CASP3CASP2CASP7CASP6 | |
| SCHEMBL12412510 | 0.78 | CYP1A2 (0.56) | PYGLHSD17B1HSD17B2CYP1A2LMNA | |
| SCHEMBL1122275 | 0.77 | HSD17B1 (0.76) | PYGLHSD17B1HSD17B2ALDH1A1CYP1A2 | |
| SCHEMBL29963136 | 0.77 | HSD17B1 (0.76) | PYGLHSD17B1HSD17B2ALDH1A1CYP1A2 | |
| SCHEMBL11594992 | 0.77 | HSD17B1 (0.55) | PYGLHSD17B1HSD17B2ALDH1A1CYP1A2 | |
| SCHEMBL4188909 | 0.75 | NLRP3 (0.59) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL29720309 | 0.75 | NLRP3 (0.59) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL10487438 | 0.75 | NT5E (0.67) | ALDH1A1CYP1A2CASP3CASP2CASP7 | |
| SCHEMBL28931475 | 0.74 | F2R (0.60) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9551029-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2017-01-24 | — | — | US | disclosed |