Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HMGCR | P04035 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14651497 | 0.88 | HMGCR (0.39) | HTR2ACYP3A4HMGCRPDE4APDE4B | |
| SCHEMBL13551182 | 0.87 | TAAR1 (0.44) | HTR2ACYP3A4HMGCRPDE4APDE4B | |
| SCHEMBL19222730 | 0.83 | ALOX5 (0.40) | HTR2AHMGCRPDE4DCYP19A1TAAR1 | |
| SCHEMBL25083003 | 0.78 | ALDH1A1 (0.54) | CYP3A4MAPTGAAHTTKDM4E | |
| SCHEMBL22545940 | 0.78 | HTR2A (0.67) | HTR2ATAAR1 | |
| SCHEMBL13547900 | 0.76 | HTR2A (0.44) | HTR2AMAPTGAATSHRMAPK1 | |
| SCHEMBL12776117 | 0.75 | TAAR1 (0.41) | HTR2AMAPTTAAR1MTNR1AMTNR1B | |
| SCHEMBL12776116 | 0.75 | TAAR1 (0.49) | HTR2AMAPTGAATSHRTAAR1 | |
| SCHEMBL74595 | 0.75 | RIPK1 (0.63) | RIPK1MAPTGAACA2TAAR1 | |
| SCHEMBL22952866 | 0.74 | TAAR1 (0.49) | HTR2AMAPTGAATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170022191-A1 | BENZAMIDES | MERCK PATENT GMBH (DE) | 2017-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022191-A1 | BENZAMIDES | FSHR, GNRHR, LHCGR | HTR2A 269/4885CYP3A4 1637/4885HMGCR 4314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.