Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18407436 | 0.80 | NOTUM (0.42) | NOTUMGAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL9468262 | 0.73 | GPR3 (0.48) | LMNAGAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL22299424 | 0.72 | KDM4E (0.57) | NOTUMGAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL67636 | 0.72 | KDM4E (0.57) | NOTUMGAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL2196564 | 0.72 | ALDH1A1 (0.37) | LMNAGAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL5835789 | 0.69 | NOTUM (0.64) | NOTUMGAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL221250 | 0.69 | NOTUM (0.64) | NOTUMGAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3134807 | 0.68 | KDM4E (0.56) | NOTUMGAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL68602 | 0.68 | KDM4E (0.56) | NOTUMGAAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL12548502 | 0.64 | KDM4E (0.49) | LMNAKDM4EALDH1A1CES1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796678-B2 | Method for manufacturing optically active compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-24 | — | — | US | disclosed |
| US-9796678-B2 | Method for manufacturing optically active compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-24 | — | — | US | disclosed |
| US-20170022162-A1 | METHOD FOR MANUFACTURING OPTICALLY ACTIVE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022162-A1 | METHOD FOR MANUFACTURING OPTICALLY ACTIVE COMPOUND | C9, C5, PRMT7 | LMNA 3744/4885NOTUM 1196/4885GAA 1195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.