SCHEMBL9468262

SCHEMBL9468262

CC1=CC(C)N(C)c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.48
PTPN2 P17706 1/20 0.38
PTPN1 P18031 1/20 0.38
KDM4E B2RXH2 8/20 0.36
ALDH1A1 P00352 7/20 0.36
GAA P10253 5/20 0.36
HPGD P15428 6/20 0.35
HSD17B10 Q99714 3/20 0.35
CASP1 P29466 2/20 0.35
GLA P06280 4/20 0.35
NPSR1 Q6W5P4 4/20 0.35
TTR P02766 1/20 0.34
CES1 P23141 1/20 0.34
ALOX12 P18054 1/20 0.34
PDGFRB P09619 1/20 0.34
LMNA P02545 3/20 0.34
TSHR P16473 3/20 0.33
RCE1 Q9Y256 2/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28399406 0.78 GPR3 (0.47) GPR3PTPN2PTPN1KDM4EALDH1A1
SCHEMBL2196564 0.76 ALDH1A1 (0.37) GPR3KDM4EALDH1A1GAAHPGD
SCHEMBL15911973 0.73 ALDH1A1 (0.36) GPR3ALDH1A1HPGDLMNATSHR
SCHEMBL18407448 0.73 LMNA (0.46) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL20495487 0.72 GPR3 (0.38) GPR3KDM4EALDH1A1GAAHPGD
SCHEMBL12548502 0.71 KDM4E (0.49) KDM4EALDH1A1HPGDTTRCES1
SCHEMBL2393562 0.68 GPR3 (0.58) GPR3PTPN2PTPN1KDM4EALDH1A1
SCHEMBL1049325 0.68 GAA (0.62) GPR3PTPN2PTPN1KDM4EALDH1A1
SCHEMBL30353863 0.68 GAA (0.62) GPR3PTPN2PTPN1KDM4EALDH1A1
SCHEMBL21250753 0.67 PDGFRB (0.46) GPR3PTPN2PTPN1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106336535-B Endless-track vehicle bogie wheel kiss-coating and preparation method thereof 济南鲁联集团橡胶制品有限公司 2018-08-10 CN claimed
CN-105367924-B Granulated plastic additive and preparation method and application thereof 中国石油天然气股份有限公司 2018-08-10 CN claimed
EP-2628162-B9 SEMICONDUCTIVE POLYMER COMPOSITION BOREALIS AG (AT) 2020-10-14 EP disclosed
EP-2628162-B1 SEMICONDUCTIVE POLYMER COMPOSITION BOREALIS AG (AT) 2020-04-22 EP disclosed
CN-105367924-B Granulated plastic additive and preparation method and application thereof 中国石油天然气股份有限公司 2018-08-10 CN disclosed
CN-103703073-B The high saturated copolymer rubber composition of nitrile group-containing 日本瑞翁株式会社 2016-07-13 CN disclosed
US-5264406-A Alkali or alkaline metal hypophosphites with amines INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1993-11-23 US disclosed
US-5264541-A Nylon 6 synthesis with water, alkali metal hypophoshite catalyst and amine cocatalyst INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1993-11-23 US disclosed
US-5260246-A Comprising alkali metal/alkaline earth hypophosphites and amine or benzotriazole cocatalysts INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1993-11-09 US disclosed
US-4419197-A PHTHALIDE PEROXIDE PEROXIDE-CHEMIE GMBH (DE) 1983-12-06 US disclosed